313 results found
    1. Neuroscience

    TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

    Christopher N Rudzitis, Monika Lakk ... David Križaj
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Neuroscience

    Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells

    Dominic Gonschorek, Matías A Goldin ... Thomas Euler
    Nitric oxide is a type-selective neuromodulator affecting the temporal, but not the spatial response kinetics of a specific subset of mouse retinal ganglion cells.
    1. Neuroscience

    Fractal cycles of sleep, a new aperiodic activity-based definition of sleep cycles

    Yevgenia Rosenblum, Mahdad Jafarzadeh Esfahani ... Martin Dresler
    Polysomnographical analysis in humans shows that temporal fluctuations of aperiodic neural activity reflect the cycling nature of sleep.
    1. Neuroscience

    Multi-dimensional oscillatory activity of mouse GnRH neurons in vivo

    Su Young Han, Shel-Hwa Yeo ... Allan E Herbison
    The gonadotropin-releasing hormone (GnRH) neurons controlling fertility exhibit abrupt increases in activity to generate luteinizing hormone (LH) pulses and a sustained oscillatory pattern of activity to generate the LH surge.
    1. Microbiology and Infectious Disease

    PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment

    Binayak Sarkar, Jyotsna Singh ... Rajesh S Gokhale
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Glucocorticoids desensitize hypothalamic CRH neurons to norepinephrine and somatic stress activation via rapid nitrosylation-dependent regulation of α1 adrenoreceptor trafficking

    Grant L Weiss, Laura M Harrison ... Jeffrey Tasker
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling

    Benjamin Le Gac, Marine Tournissac ... Bruno Cauli
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development

    Denise M Poltavski, Alexander T Cunha ... Takako Makita
    Neural crest and placode lineages both contribute to the enteric nervous system, divergently utilizing Edn3-Ednrb and GDNF-Ret signaling.
    1. Microbiology and Infectious Disease

    Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans

    Catia Mota, Kiseung Kim ... Hyun Ah Kang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

    Julieta Gomez-Frittelli, Gabrielle Devienne ... Julia A Kaltschmidt
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
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