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The crosstalk between cancer cell genomic features and the tumor microenvironment (TME) to reveal the impact of genetic alterations on the TME phenotype.

Mu and delta opioid receptors signal independently in hippocampal parvalbumin interneurons to regulate somato-dendritic excitability and synaptic transmission, with the delta opioid receptor dominating the response to enkephalin.

Simultaneous recordings in brainstem and cortex, combined with pupillometry, show that changes in coordinated activity in anterior cingulate cortex are related to distinct patterns of pupil-linked activation of the locus coeruleus-norepinephrine system.

After an injury to the skin, murine wounds upregulate apoptosis and efferocytosis pathways, which are required for effective healing and may similarly impact wound healing in diabetic patients.

Transcription factors downstream of Hippo signaling control formation of the Left-Right Organizer by regulating major signaling pathways, expression of transcription factors and regulators of epigenetic programming involved in this process.

Resting natural killer cells promote the progress of colon cancer liver metastasis (CCLM), which may be exploited for novel strategies to improve therapeutic outcomes for patients with CCLM.

The Tsr2 carrier protein connects the nuclear import machinery with the ribosome assembly pathway.

Spinal stimulation at balanced currents of excitation and inhibition boosts voluntarily produced torque production.

Traumatic injury leads to functional defects in nucleocytoplasmic transport and TDP-43 pathology in multiple model systems.