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    1. Neuroscience

    Behavioral entrainment to rhythmic auditory stimulation can be modulated by tACS depending on the electrical stimulation field properties

    Yuranny Cabral-Calderin, Daniela van Hinsberg ... Molly J Henry
    Transcranial alternating current stimulation modulates behavioral entrainment to sounds.
    1. Chromosomes and Gene Expression

    Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters

    Yi-Jun Sheu, Risa Karakida Kawaguchi ... Bruce Stillman
    The localization of Rad53 cell cycle checkpoint kinase to many gene promoters and the dynamic changes in response to replication stress suggests that the kinase may coordinate genome stability and gene expression.
    1. Biochemistry and Chemical Biology

    The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

    Valentin Bohl, Nele Merret Hollmann ... Axel Mogk
    The bacterial AAA+ chaperone ClpL recognizes aggregated proteins via multiple contacts of its unique N-terminal domain and refolds them with high efficiency providing superior heat resistance.
    1. Structural Biology and Molecular Biophysics

    Structure of mycobacterial CIII2CIV2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203)

    David J Yanofsky, Justin M Di Trani ... John L Rubinstein
    The structure of the Mycobacterium smegmatis CIII2CIV2 respiratory supercomplex with telacebec (Q203) bound shows how this tuberculosis drug candidate blocks respiration in mycobacteria.
    1. Neuroscience
    2. Physics of Living Systems

    Gigapixel imaging with a novel multi-camera array microscope

    Eric E Thomson, Mark Harfouche ... Eva A Naumann
    A new multi camera imaging platform simultaneously captures large-area, high-resolution video of unconstrained small model organisms and provides behavioral measurements that span multiple spatial scales.
    1. Cell Biology
    2. Physics of Living Systems

    Cortical waves mediate the cellular response to electric fields

    Qixin Yang, Yuchuan Miao ... Wolfgang Losert
    Electrical and biomechanical stimuli directly bias cortical signal transduction and cytoskeletal waves, and the direct bias induced by an electric field develops slowly compared to the rapid surface-receptor-mediated response to chemotactic gradients.
    1. Neuroscience

    GABAergic synaptic scaling is triggered by changes in spiking activity rather than AMPA receptor activation

    Carlos Gonzalez-Islas, Zahraa Sabra ... Peter Wenner
    Chronic perturbations of spiking activity trigger compensatory changes in GABAergic synaptic strength, but not compensatory changes in AMPAergic synaptic strength.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel

    Peter R Strege, Luke M Cowan ... Arthur Beyder
    Force applied to the cell membrane reversibly changes a voltage-insensitive gating step of a prokaryotic voltage-gated sodium channel.
    1. Neuroscience

    Voluntary and involuntary contributions to perceptually guided saccadic choices resolved with millisecond precision

    Emilio Salinas, Benjamin R Steinberg ... Terrence R Stanford
    Looking away from a salient visual stimulus pits the reflexive urge to look toward it against the voluntary intention not to, and this conflict is resolved within tens of milliseconds.
    1. Computational and Systems Biology
    2. Neuroscience

    BrainPy, a flexible, integrative, efficient, and extensible framework for general-purpose brain dynamics programming

    Chaoming Wang, Tianqiu Zhang ... Si Wu
    BrainPy presents a general-purpose programming framework that enables efficient implementation, simulation, training, and analysis of brain dynamics models across multiple organization scales, ultimately facilitating the understanding of the complex neural mechanisms underlying brain functions.