240 results found
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome

    Laura A Lavery et al.
    Dnmt3a regulates gene expression in inhibitory neurons by writing all mCH and some mCG, and MeCP2 reads some of these mCH sites driving a portion of these gene expression changes.
    1. Genetics and Genomics
    2. Plant Biology

    DNA Methylation: Epigenetics in the wild

    Adam J Bewick , Robert J Schmitz
    Insight
    Available as:
    • HTML
    • PDF
    1. Developmental Biology
    2. Genetics and Genomics

    2018 Gairdner Awards: The discovery and importance of genomic imprinting

    Anne C Ferguson-Smith, Deborah Bourc'his
    Research into genomic imprinting has provided a foundation for the study of epigenetic mechanisms, especially during development, and has also shed light on a range of rare genetic disorders and common diseases.
    1. Ecology
    2. Evolutionary Biology
    House sparrow illustration

    The Natural History of Model Organisms: The house sparrow in the service of basic and applied biology

    Haley E Hanson et al.
    The house sparrow, one of the most ubiquitous birds in the world, is now used extensively in studies across disciplines in the life sciences.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Science Forum: Considerations when investigating lncRNA function in vivo

    Andrew R Bassett et al.
    We discuss the methods available to understand lncRNA function in vivo, and highlight important considerations that should be taken into account when designing such experiments.
    1. Cell Biology

    Epigenetics: How does obesity lead to insulin resistance?

    Chan Hee J Choi, Paul Cohen
    Experiments on mice show that an enzyme called DNA methyltransferase 3a is involved in insulin resistance via an epigenetic mechanism.
    Insight
    Available as:
    • HTML
    • PDF
    1. Chromosomes and Gene Expression
    2. Plant Biology

    The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status

    Dongming Li et al.
    The METHYL-CpG-BINDING DOMAIN 7 (MBD7) complex promotes the activation (rather than repression) of transgenes that undergo DNA methylation and it does so without significantly altering their methylation status, placing this complex downstream of DNA methylation.

Refine your results by:

Type
Research categories