2,952 results found
    1. Neuroscience

    Macro-connectomics and microstructure predict dynamic plasticity patterns in the non-human primate brain

    Sean Froudist-Walsh et al.
    Brain recovery after injury can be predicted based on its activity and structure, which may allow us to understand why some brain injuries lead to permanent loss of cognitive function, while others do not.
    1. Neuroscience

    Targeted cortical reorganization using optogenetics in non-human primates

    Azadeh Yazdan-Shahmorad et al.
    Focal optogenetic stimulation strengthens functional connectivity between primary somatosensory and motor cortices in macaques, in a manner consistent with a Hebbian model of stimulus-driven plasticity.
    1. Microbiology and Infectious Disease

    Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir

    Alex C Stabell et al.
    An analysis of innate immunity reveals why dengue viruses do not reach high titers in primate laboratory models, even though they emerged through zoonotic transmission from primate reservoirs.
    1. Developmental Biology

    Species-specific maturation profiles of human, chimpanzee and bonobo neural cells

    Maria C Marchetto et al.
    Using iPSCs as a model to study neurodevelopmental differences between human and nonhuman primates lays the groundwork for understanding aspects of human brain evolution and neurological disease susceptibility.
    1. Neuroscience

    Inferring eye position from populations of lateral intraparietal neurons

    Arnulf BA Graf, Richard A Andersen
    An area of visual-motor cortex called the lateral intraparietal area encodes eye position signals that support visually-guided behaviors and image stabilization.
    1. Neuroscience

    Neuronal representation of saccadic error in macaque posterior parietal cortex (PPC)

    Yang Zhou et al.
    Neurons in the macaque posterior parietal cortex behave like an error detector that computes the saccadic error by comparing the intended and the actual saccade end-position signals.
    1. Computational and Systems Biology

    Distributed task-specific processing of somatosensory feedback for voluntary motor control

    Mohsen Omrani et al.
    Somatosensory feedback is transmitted to many sensory and motor cortical regions within 25 milliseconds and ongoing behavioural tasks alter the spatiotemporal pattern of this perturbation-related activity, supporting rapid motor responses to attain behavioural goals.
    1. Neuroscience

    Inhibition of protein synthesis in M1 of monkeys disrupts performance of sequential movements guided by memory

    Machiko Ohbayashi
    Inhibition of protein synthesis in primary motor cortex (M1) of monkeys disrupted the performance of skilled sequential movements suggesting that M1 is involved in maintenance of skilled sequential movements.
    1. Neuroscience

    A selective role for ventromedial subthalamic nucleus in inhibitory control

    Benjamin Pasquereau, Robert S Turner
    Single-unit activity consistent with a selective causal role in reactive stopping or switching behaviors is found only in the most ventromedial subregion of the subthalamic nucleus.
    1. Cancer Biology
    2. Cell Biology

    EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells

    Benjamin Krusche et al.
    EphrinB2 promotes glioblastoma stem-like cell malignancy through the interplay of cell-autonomous and non-cell-autonomous mechanisms and its targeting suppresses tumourigenesis in preclinical models of human glioblastoma.

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