4,708 results found
    1. Neuroscience

    Tuning of olfactory cortex ventral tenia tecta neurons to distinct task elements of goal-directed behavior

    Kazuki Shiotani et al.
    Individual neurons of ventral tenia tecta which is a part of olfactory cortex tune to specific time windows in the behavioral context during odor-guided goal-directed behaviors.
    1. Developmental Biology
    2. Medicine

    RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1

    Md Rakibul Hasan et al.
    RAB23 regulates calvarial bone and suture development both independently through, and by cross-talk between, Hedgehog and fibroblast growth factor signaling.
  1. Research Culture: Changing how we evaluate research is difficult, but not impossible

    Anna Hatch, Stephen Curry
    The DORA initiative offers practical guidance on improving the assessment of research by universities, research institutions, and funders.
    1. Computational and Systems Biology
    2. Neuroscience

    The head direction circuit of two insect species

    Ioannis Pisokas et al.
    Two evolutionary distant insect species share a common head direction circuit with subtle differences in neuronal morphologies that result in distinct circuit dynamics adapted to each species’ ecology.
    1. Structural Biology and Molecular Biophysics

    Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter

    Julia Steiner, Leonid Sazanov
    Structure of the Mrp antiporter, an ancestor of respiratory complex I, suggests a mechanism of coupling between cation and proton translocation, applicable to a large family of related membrane proteins.
    1. Ecology
    2. Evolutionary Biology

    Caterpillar-induced rice volatiles provide enemy-free space for the offspring of the brown planthopper

    Xiaoyun Hu et al.
    The brown planthopper has evolved a highly adaptive oviposition strategy by exploiting caterpillar-induced plant volatiles that provide safe havens for its offspring.
    1. Microbiology and Infectious Disease

    MARCH8 inhibits viral infection by two different mechanisms

    Yanzhao Zhang et al.
    The host transmembrane protein MARCH8, previously known as an expression regulator of host proteins, is a powerful antiviral host factor with a potentially broad antiviral spectrum through two different mechanisms.
    1. Developmental Biology
    2. Genetics and Genomics

    Odd-paired is a pioneer-like factor that coordinates with Zelda to control gene expression in embryos

    Theodora Koromila et al.
    The gene Odd-paired is a late-acting regulator of zygotic gene expression, functioning coordinately with Zelda to influence chromatin accessibility and affecting genes expressed along both axes of Drosophila embryos.
    1. Cell Biology
    2. Immunology and Inflammation

    Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex

    Daniel Blumenthal et al.
    The dendritic cell actin cytoskeleton provides a platform for T cell mechanosensing, delivering novel biophysical cues that serve as costimulatory signals for T cell activation.
    1. Neuroscience

    Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination

    Cristina Blázquez et al.
    Δ9-Tetrahydrocannabinol impairs motor coordination in mice by inhibiting autophagy in the striatonigral pathway, thus defining a new conceptual view of how cannabis acts in the brain.

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