Browse the search results

Page 2 of 380
    1. Neuroscience

    Complementary encoding of priors in monkey frontoparietal network supports a dual process of decision-making

    Lalitta Suriya-Arunroj, Alexander Gail
    Probability of upcoming actions modulates subclasses of neurons in frontoparietal motor-planning areas in a complementary fashion and frontal-lobe processing takes the leading role when primates commit to a decision.
    1. Plant Biology

    Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID

    Andrea Mair et al.
    Proximity-labeling using engineered biotin ligases TurboID and miniTurbo enables detection of cell-type-specific and low abundance protein complexes and subcellular proteomes in Arabidopsis and other plants.
    1. Cancer Biology
    2. Developmental Biology

    Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors

    Sara Genovese et al.
    About twenty temporal patterning genes are identified that drive an irreversible differentiation trajectory governing the heterogeneity and proliferative properties of cells in neural tumors with an early developmental origin.
    1. Structural Biology and Molecular Biophysics

    Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states

    Amanda F Clouser et al.
    Multiple iso-energetic-specific interactions involving the intrinsically-disordered region of sHSP HSPB1 define a quasi-ordered state, providing insights into inherited disease-associated mutations within the region that are thought to be disordered.
    1. Microbiology and Infectious Disease

    Transcriptome dynamics of the Myxococcus xanthus multicellular developmental program

    José Muñoz-Dorado et al.
    Investigation of global gene expression profiles during formation of the Myxococcus xanthus specialized biofilm reveals a genetic regulatory network that coordinates cell motility, differentiation, and secondary metabolite production.
    1. Neuroscience

    Brian 2, an intuitive and efficient neural simulator

    Marcel Stimberg et al.
    Brian 2 is a software package for neural simulations that makes it both easy and computationally efficient to define original models for computational experiment.
    1. Developmental Biology

    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

    Elif Kon et al.
    FGFRs regulate multipolar cortical neuron orientation and the morphological change into bipolar cells in vivo under the control of N-Cadherin and the extracellular matrix protein Reelin.
    1. Cell Biology
    2. Developmental Biology

    BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryogenesis

    Hyung-Seok Kim et al.
    Endogenous BMP2/7 and BMP4/7 heterodimers form in vivo, and are the predominant functional ligand in many, if not all, tissues of developing mouse embryos.
    1. Developmental Biology

    Taste bud formation depends on taste nerves

    Di Fan et al.
    The sensory nerves that carry sensations from the taste buds to the brain induce the formation of the taste buds in the embryo.
    1. Microbiology and Infectious Disease

    Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii

    Alex Hunt et al.
    Partially overlapping functions of a limited subset of actin binding proteins allow the parasite Toxoplasma gondii to achieve actin regulation required for complex cellular processes.