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    1. Neuroscience

    Pull-push neuromodulation of cortical plasticity enables rapid bi-directional shifts in ocular dominance

    Su Hong et al.
    Neuromodulation of the expression of Hebbian plasticity enables rapid cortical sensory-induced remodeling in post-critical period adults, and can rescue deficits induced by prolonged sensory deprivation.
    1. Developmental Biology
    2. Genetics and Genomics

    Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice

    Mohamed Mahgoub et al.
    The meiotic recombination landscape in vertebrates was re-engineered via the co-evolution of a dual histone H3K4/H3K36 methylation 'writer' PRDM9 and its 'reader' ZCWPW1 that facilitates efficient double strand break repair.
    1. Neuroscience

    LKB1 coordinates neurite remodeling to drive synapse layer emergence in the outer retina

    Courtney A Burger et al.
    LKB1 instructs the timing and location of synapse layer emergence in the outer retina by coordinating the regulation of pre- and postsynaptic neuron maturation and transport of synapse-associated proteins.
    1. Cell Biology

    Serotonin signaling by maternal neurons upon stress ensures progeny survival

    Srijit Das et al.
    Neuronal serotonin release tunes transcription response times of Caenorhabditis elegans germ cells to promote the survival and stress resistance of future offspring.
    1. Developmental Biology
    2. Genetics and Genomics

    OTX2 represses sister cell fate choices in the developing retina to promote photoreceptor specification

    Miruna Georgiana Ghinia Tegla et al.
    A retinal gene regulatory network prevents the formation of alternative cell fates from non-stochastic retinal progenitor cells.
    1. Ecology

    Modelling the climatic suitability of Chagas disease vectors on a global scale

    Fanny E Eberhard et al.
    The global ensemble forecasting niche modelling of 11 vector competent triatomine species revealed climatic suitable regions outside their native distribution including the cosmopolitan vector Triatoma rubrofasciata.
    1. Neuroscience

    The sifting of visual information in the superior colliculus

    Kyu Hyun Lee et al.
    The superior colliculus reveals hallmarks of sophisticated visual computation, including selectivity, invariance, and stimulus-specific habituation to behaviorally relevant stimuli.
    1. Ecology

    Rarity is a more reliable indicator of land-use impacts on soil invertebrate communities than other diversity metrics

    Andrew Dopheide et al.
    Rarity metrics reveal pervasive negative impacts of agricultural land use on soil invertebrate communities, whereas widely-used richness and diversity metrics underestimate the magnitude of these impacts.
    1. Physics of Living Systems

    Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo

    Elizabeth R Jerison, Stephen R Quake
    Motile interstitial T cells in live zebrafish access a broad range of length-scales due to long-lived cell-intrinsic variation in speed, and a coupling between speed and directional persistence.
    1. Neuroscience

    Acetylcholine acts on songbird premotor circuitry to invigorate vocal output

    Paul I Jaffe, Michael S Brainard
    The neuromodulator acetylcholine contributes to state-dependent modulation of motor vigor and variability by direct action on songbird premotor cortex, bypassing basal ganglia circuitry.