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A novel machine learning approach improves quantitative comparisons of mouse and human brains using spatial transcriptomics data sets.

Non-invasive disinhibition of the oculomotor system shows that ongoing preparatory activity in the superior colliculus has movement-generating potential and need not rise to threshold in order to produce a saccade.

Sulforaphane through NRF2-dependent and -independent cellular and molecular pathways alleviates leptin resistance to reverse the diet-induced obesity.

Cross-frequency synchronization of neuronal oscillations in visual and attentional brain systems predicts human working memory performance.

AMP-activated protein kinase directly coordinates glutamatergic signalling during starvation in C. elegans.

Depletion of PHF19 in prostate cancer cells leads to an increase in MTF2 and PRC2 chromatin occupancy causing deregulation of key genes critical for proliferation and metastasis.

Amyloid beta, the major component of plaques in Alzheimer's disease, acutely and reversibly signals to modulate sleep as a function of oligomeric length, independently of neuronal loss.