Reactive endothelial venules are a new vessel subtype characterized by consistent expression of cell adhesion molecules, preferential leukocyte transmigration, association with perivascular macrophages, and the initiation of CNS immune responses.

Dephosphorylation of Notch1 intracellular domain by Eya1 leads to enhanced Notch signalling activity in the non-neuronal epibranchial placodal cells, revealing an essential regulation for the formation of proximal pharyngeal arches during mouse craniofacial development.

Single cell RNA–sequencing and neuroanatomical methods reveal unexpected molecular diversity and highly segregated spatial organization of neuronal cell types within the mouse ventral posterior hypothalamus, including the mammillary nuclei.

Identification of transcriptional changes in the hypothalamus during Influenza A virus infection enhances our understanding of mechanisms underlying long-lasting neurological disturbances, potentially informing future therapeutic interventions and improving patient outcomes.

Extracellular vesicles are proposed as novel, non-cell-autonomous mediators of neuronal atrophy in Parkinson's disease.

Precisely sequenced patterns of neuronal activity associated with the production of a skilled behavior begin and end as part of orchestrated activity across functionally diverse populations of cortical premotor neurons.

Reconstruction of cell-type families in the purple sea urchin larva reveals unprecedented transcriptional diversity, stunning neuronal complexity and a missing link to pancreas evolution, suggesting this approach can be also used to uncover hidden cell type homologies.

Large-scale imaging analysis of CA1 reveals that distinct neural networks are involved in trace conditioning versus extinction learning, shedding light on how the hippocampus encodes different types of memory.

Unbiased computational integration of single-cell- and human genetics data shows that susceptibility to obesity is driven by a broad set of neuronal populations across the brain.

Short-ranged and random connectivity are sufficient to explain complex, long-range activity patterns observed in macaque motor cortex that are, moreover, flexibly adaptable to behavior.