Emily R Ebel, Frans A Kuypers ... Elizabeth S Egan
Human red blood cells from healthy donors display marked biophysical and genetic variation that impacts the growth of Plasmodium falciparum malaria parasites, outside of known disease alleles.
A spiking network model that examines the transformation of odor information from olfactory bulb to piriform cortex demonstrates how intrinsic cortical circuitry preserves representations of odor identity across odorant concentrations.
Stephan Kamrad, María Rodríguez-López ... Jürg Bähler
An open-source python package for phenotype analyses provides a versatile, modular and user-friendly solution to determine complementary fitness-related traits from large-scale assays of microbial colonies.
Ching Fang, Dmitriy Aronov ... Emily L Mackevicius
A recurrent network using a simple, biologically plausible learning rule can learn the successor representation, suggesting that long-horizon predictions are computations that are easily accessible in neural circuits.
Heterochromatin is established at nucleation sites associated with open chromatin and RNA transcripts and matures into stable domains if they are found near transposable elements targeted by maternally deposited piRNAs.
Local disinhibition provides a biologically plausible mechanism for flexible top-down control of network states that integrates normalized value coding, winner-take-all choice, and persistent activity in a single circuit of decision-making.
Avital Hahamy, Stamatios N Sotiropoulos ... Tamar R Makin
Building on previous work (Makin et al., 2013), we show that the brains of individuals born without a hand adaptively change to compensate for their disability.