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    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Piezo Ion Channels: Portraits of a pressure sensor

    Alexander T Chesler, Marcin Szczot
    Near atomic-resolution structures have provided insights into the mechanisms by which the Piezo1 ion channel senses and responds to mechanical stimuli.
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    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
  1. Point of View: Four erroneous beliefs thwarting more trustworthy research

    Mark Yarborough et al.
    Strategies to improve public trust in biomedical research are being hindered by a scientific mindset that stifles interest in reform.
    1. Computational and Systems Biology

    Meta-Research: Releasing a preprint is associated with more attention and citations for the peer-reviewed article

    Darwin Y Fu, Jacob J Hughey
    An analysis of more than 70,000 journal articles, including 5405 that were first released as a preprint on bioRxiv, shows that articles with a preprint received 49% more attention and 36% more citations than articles without one.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Immunodeficiency: Back from the brink of obscurity

    Donald C Vinh
    A mutation in a transcription factor makes people susceptible to Trophyrema whippelii, the bacterium that causes a rare condition called Whipple's disease.
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  2. Research: Sci-Hub provides access to nearly all scholarly literature

    Daniel S Himmelstein et al.
    The availability of almost all articles from toll access journals in the Sci-Hub repository will disrupt scholarly publishing towards more open models.
  3. Plain-language Summaries of Research: Something for everyone

    Sarah Shailes
    Journals and other scientific organizations produce a diverse variety of plain-language summaries.
    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: New opportunities at the wild frontier

    Jane Alfred, Ian T Baldwin
    A better understanding of the natural history of model organisms will increase their value as model systems and also keep them at the forefront of research.
    1. Neuroscience

    Sleep: Up all night on a redeye flight

    Leslie C Griffith
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    1. Evolutionary Biology

    Stem Cells: Getting to the heart of cardiovascular evolution in humans

    Alex Pollen, Bryan J Pavlovic
    Differences in the response of cardiomyocytes to oxygen deprivation in humans and chimpanzees may explain why humans are more prone to certain heart diseases.
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