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In chick skeletal muscle, an incoming signal leads to two interdependent outcomes: a cell fate change and an epithelial-mesenchymal transition.

The Notch signaling pathway has a central role in the development of the nervous system, and also in the establishment of networks of connections in the adult brain

A novel mechanism links mechanical signals with the molecular YAP and NOTCH signals operating during developmental myogenesis.

The Notch signaling pathway has a central role in the formation of the circuit that controls egg-laying in the nematode worm C. elegans.

Angiopoietin-like proteins signal through notch via receptor interaction and can regulate Notch cleavage/activation.

In adult mouse hippocampus, neural stem cell and their progeny communicate via Lunatic Fringe mediated Notch signaling to regulate stem cell quiescence, division, and fate.

While Notch activation dedifferentiates newly differentiated muscle cells; it improves the function of muscle fiber as a niche-supporting cell of muscle stem cells.

Notch signaling in human platelets functions in noncanonical juxtacrine manner to amplify platelet reactivity and thrombogenicity.

T cell receptor and Notch signaling pathways are linked via a novel mechanism involving modulation of the cytoskeleton.