A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.

An interaction between two proteins enables the spindle—the structure that segregates chromosome pairs during mitosis—to change size as cells divide.

Individual granule cells within the cerebellum-the region of the brain that coordinates movement and supports the learning of new motor skills-receive both sensory and motor input streams: an arrangement that may help the brain to use feedback to fine-tune movement.

Sensory neurons in the olfactory system develop from two different regions of the ectoderm, the olfactory placode and the cranial neural crest, whereas sensory neurons within the eye and ear develop from just one region.

A gene that codes for a transcription factor that is involved in lipid and carbohydrate metabolism also has a role in the regulation of circadian rhythms.

Ubiquitin ligase adaptors target the selective clearance of misfolded plasma membrane proteins.

Secretory cells in the fruit fly reproductive tract produce secretions that control ovulation through a conserved mechanism that could provide insights into ovarian cancer.

The strain of Phytophthora infestans that caused the Great Famine in the late 1840s was caused by a single genotype that is distinct from, but closely related to, the most prevalent modern genotype.

Lysine-specific demethylase 1 (Lsd1) has an essential role during both the early and later stages of blood cell development.

Nutrient limitation elicits differential responses in cells lacking the tumor suppressor PTEN and in normal cells, resulting in hyperplastic overgrowth of PTEN mutant tissue independent of additional mutations.