3,077 results found
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock

    Andrea Brenna et al.
    Cyclin-dependent kinase 5 regulates the circadian clock involving phosphorylation of the PER2 protein.
    1. Plant Biology

    Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID

    Andrea Mair et al.
    Proximity-labeling using engineered biotin ligases TurboID and miniTurbo enables detection of cell-type-specific and low abundance protein complexes and subcellular proteomes in Arabidopsis and other plants.
    1. Genetics and Genomics

    Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

    Bianca Hartmann et al.
    Mutations affecting a nuclear encoded metalloprotease cause of a new form of mitochondriopathy, highlighting the importance of this protease for mitochondrial function in humans.
    1. Microbiology and Infectious Disease

    Biofilms: Take my breath away

    Vinai C Thomas, Paul D Fey
    A lack of oxygen activates a pathway that causes the bacterial cell wall to break down, which, in turn, aids bacterial biofilm development.
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    1. Microbiology and Infectious Disease

    Research: A comprehensive and quantitative exploration of thousands of viral genomes

    Gita Mahmoudabadi, Rob Phillips
    A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Tumor Angiogenesis: Taking aim at Sox18

    Injune Kim, Gou Young Koh
    A small molecule called Sm4 can disrupt interactions involving a transcription factor called Sox18, while having little impact on other members of the SoxF family.
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    1. Cell Biology

    Unfolded Protein Response: Modulating protein quality control

    Lars Plate et al.
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    1. Structural Biology and Molecular Biophysics

    Protein Unfolding: Same structure, different mechanisms?

    Francis TF Tsai, Christopher P Hill
    Two interpretations of similar structures for the same molecular machine illustrate the limits of inferring biochemical mechanism from protein structure.
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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: SARS-CoV-2 (COVID-19) by the numbers

    Yinon M Bar-On et al.
    Key numbers about the biology of the SARS-CoV-2 virus and the infection of a single human host by the virus have been compiled from the peer-reviewed literature.

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