2,843 results found
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock

    Maria Azkanaz et al.
    Heat shock induces relocalization of epigenetic modifiers to the nucleolus, which acts as a dedicated protein quality control center that is indispensable for recovery of epigenetic regulators and epigenetic modifications.
    1. Structural Biology and Molecular Biophysics

    Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

    Diana M Mitrea et al.
    Nucleolar protein localization involves the phase separation within the nucleolar matrix via three types of multivalent features: acidic tracts, nucleic acid binding domains and arginine-rich low complexity sequences.
    1. Neuroscience

    Human subthalamic nucleus activity during non-motor decision making

    Baltazar A Zavala et al.
    Intraoperative human brain recordings during a memory task reveal that when participants inhibit memory formation, the subthalamic nucleus shows higher beta power and beta coherence with areas of the lateral cortex implicated in memory processing.
    1. Neuroscience

    Subthalamic nucleus gamma activity increases not only during movement but also during movement inhibition

    Petra Fischer et al.
    Sudden stopping of rhythmic movement is associated with a pronounced increase of 60-90 Hz gamma oscillations in the subthalamic nucleus, which have formerly been regarded as favouring movement.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Nucleolar dynamics and interactions with nucleoplasm in living cells

    Christina M Caragine et al.
    The nucleoplasm surrounding nucleoli in living cells plays a key role in nucleolar dynamics and shape fluctuations in vivo.
    1. Neuroscience

    Revealing a novel nociceptive network that links the subthalamic nucleus to pain processing

    Arnaud Pautrat et al.
    The subthalamic nucleus is linked to a nociceptive network and involved in nociceptive processing and perception.
    1. Neuroscience

    Molecular and anatomical organization of the dorsal raphe nucleus

    Kee Wui Huang et al.
    The dorsal raphe nucleus contains transcriptionally diverse cell classes that include subtypes of serotonergic neurons with distinct molecular and anatomical signatures.
    1. Neuroscience

    Leptin increases sympathetic nerve activity via induction of its own receptor in the paraventricular nucleus

    Zhigang Shi et al.
    Leptin acts in the paraventricular nucleus to slowly increase sympathetic nerve activity to skeletal muscle and brown adipose tissue via induction of its own receptor in TRH glutamatergic neurons.
    1. Neuroscience

    Dorsal raphe nucleus to anterior cingulate cortex 5-HTergic neural circuit modulates consolation and sociability

    Laifu Li et al.
    Inhibition of 5-HT neurons in the dorsal raphe nuclei or 5-HT terminals in the anterior cingulate cortex decreased consolation-like behaviors and reduced sociability.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Single nucleus sequencing reveals evidence of inter-nucleus recombination in arbuscular mycorrhizal fungi

    Eric CH Chen et al.
    Arbuscular mycorrhizal fungi generate nuclear diversity in the dikaryotic life-stage stage via inter-nucleus recombination.

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