Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum, are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.

Lactobacillus plantarum regulates host uric acid metabolism via its own nucleoside hydrolase iunH.

Biochemical and structural analyses reveal direct ubiquitin modification of single-stranded nucleic acids, catalysed by the DTX3L ubiquitin ligase.

First high-resolution structure of HGSNAT-acetyl-CoA complex, that describes the architecture of a novel transmembrane N-acetyltransferase fold and provides a molecular basis for MPS IIIC causing mutation induced destabilization of HGSNAT.

A comprehensive description of gene expression and organisation in the cells that constitute the blood fluke larvae responsible for finding and invading its intermediate host.

Targeted manipulations on organotypic cultures show that the retina switches between at least four different metabolic pathways, each with different yields and kinetics, to dynamically adapt to momentaneous energy needs.

Purine recycling deficiency triggers metabolic and neurological defects reminiscent of Lesch–Nyhan disease in Drosophila, paving the way for studying this disorder and carrying out drug screening in an invertebrate organism.