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    1. Neuroscience

    Brainstem network dynamics underlying the encoding of bladder information

    Anitha Manohar, Andre L Curtis ... Rita J Valentino
    Neural and network activity within a pontine-cortical micturition circuit are finely coordinated with urodynamics to assure appropriate voiding behaviors.
    1. Ecology

    Deciphering deep-sea chemosynthetic symbiosis by single-nucleus RNA-sequencing

    Hao Wang, Kai He ... Chaolun Li
    A cellular map of a deep-sea mussel gill unveils how distinct cell types collaborate to cultivate intracellular symbiotic bacteria, providing insights into host–symbiont interactions and environmental adaptation in bivalves.
    1. Developmental Biology

    An adhesion G protein-coupled receptor is required in cartilaginous and dense connective tissues to maintain spine alignment

    Zhaoyang Liu, Amro A Hussien ... Ryan S Gray
    The regulation of the biomechanical properties of tendons/ligaments is essential for the maintenance of spine alignment in the mouse.
    1. Neuroscience

    Mixed representations of choice direction and outcome by GABA/glutamate cotransmitting neurons in the entopeduncular nucleus

    Julianna Locantore, Yijun Liu ... Michael Wallace
    Basal ganglia output from the entopeduncular nucleus to the lateral habenula is not required for performance in a probabilistic switching task that requires flexible action/outcome decision making.
    1. Neuroscience

    Human subthalamic nucleus activity during non-motor decision making

    Baltazar A Zavala, Anthony I Jang, Kareem A Zaghloul
    Intraoperative human brain recordings during a memory task reveal that when participants inhibit memory formation, the subthalamic nucleus shows higher beta power and beta coherence with areas of the lateral cortex implicated in memory processing.
    1. Medicine
    2. Neuroscience

    Lead-OR: A multimodal platform for deep brain stimulation surgery

    Simón Oxenford, Jan Roediger ... Andreas Horn
    Lead-OR visualizes results derived from microelectrode recordings in anatomical space, together with information derived from patient-specific MRI data, as well as high-resolution atlas resources during deep brain stimulation surgery.
    1. Cell Biology
    2. Computational and Systems Biology

    Quantitative live-cell imaging and computational modeling shed new light on endogenous WNT/CTNNB1 signaling dynamics

    Saskia MA de Man, Gooitzen Zwanenburg ... Renée van Amerongen
    Genome editing, advanced live-cell microscopy, and computational modeling were combined to measure WNT/CTNNB1 signaling parameters at the single molecule level, revealing critical regulatory nodes in this important signal transduction pathway.
    1. Medicine

    Brain atlas for glycoprotein hormone receptors at single-transcript level

    Vitaly Ryu, Anisa Gumerova ... Mone Zaidi
    The most comprehensive neuroanatomical atlas on the expression of three glycoprotein hormone receptors, namely, TSHRs, LHCGRs, and FSHRs, was mapped using RNAscope, a technology that allows the detection of mRNA at single-transcript level.
    1. Neuroscience

    No evidence from complementary data sources of a direct glutamatergic projection from the mouse anterior cingulate area to the hippocampal formation

    Lilya Andrianova, Steliana Yanakieva ... Michael T Craig
    A combination of anterograde and retrograde anatomical-tracing methods failed to provide evidence of a recently described projection from the anterior cingulate area to the hippocampus.
    1. Developmental Biology
    2. Plant Biology

    Opposite polarity programs regulate asymmetric subsidiary cell divisions in grasses

    Dan Zhang, Roxane P Spiegelhalder ... Michael T Raissig
    The formation of stomatal 'helper cells' (=subsidiary cells) in grasses requires two opposing polarity domains with diverse roles in establishing division asymmetry.