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    1. Biochemistry and Chemical Biology

    Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex

    Ming-Feng Tsai, Charles B Phillips ... Christopher Miller
    Studies of EMRE, one of the four essential protein subunits in the mitochondrial calcium uniporter complex that regulates calcium ion levels in mitochondria, reveal new details about the physical interactions between the subunits.
    1. Plant Biology

    The chloroplast 2-cysteine peroxiredoxin functions as thioredoxin oxidase in redox regulation of chloroplast metabolism

    Mohamad-Javad Vaseghi, Kamel Chibani ... Karl-Josef Dietz
    The chloroplast 2-cysteine peroxiredoxin is central player and missing link in the chloroplast thiol-disulfide redox regulatory network, and participates in oxidative inactivation of reductively activated enzymes in photosynthesis.
    1. Neuroscience

    Regional response to light illuminance across the human hypothalamus

    Islay Campbell, Roya Sharifpour ... Gilles Vandewalle
    Distinct local dynamics of different hypothalamus areas were detected in response to changing illuminance and could contribute to light’s impact on cognition.
    1. Cell Biology

    Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination

    Eric Seemann, Minxuan Sun ... Britta Qualmann
    Mice lacking the membrane-shaping protein syndapin III show severe reduction of caveolae reminiscent of human caveolinopathies but maintain plasma membrane-associated caveolar coats proteins and thereby unveil physiological impairments associated with lack of invaginated caveolae.
    1. Neuroscience

    A neuronal least-action principle for real-time learning in cortical circuits

    Walter Senn, Dominik Dold ... Mihai A Petrovici
    A principle from which the neuronal dynamics and synaptic plasticity in arbitrary network architectures can be inferred, so that output errors are online minimized while simultaneously processing sensory input streams.
    1. Cell Biology
    2. Immunology and Inflammation

    Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex

    Daniel Blumenthal, Vidhi Chandra ... Janis K Burkhardt
    The dendritic cell actin cytoskeleton provides a platform for T cell mechanosensing, delivering novel biophysical cues that serve as costimulatory signals for T cell activation.
    1. Neuroscience

    A connectomics-based taxonomy of mammals

    Laura E Suarez, Yossi Yovel ... Bratislav Misic
    Inter-species variations in connectome architecture across the mammalian phylogenetic spectrum recapitulate established taxonomic relationships defined by genetic, morphology, and behavioural differences, and are mainly driven by local changes in connectivity while hallmark global features tend to be conserved across species.
    1. Neuroscience

    Distinct neural networks for the volitional control of vocal and manual actions in the monkey homologue of Broca's area

    Natalja Gavrilov, Andreas Nieder
    Single-neuron recordings in the inferior frontal cortex of trained macaques show neurons that are selective to the volitional preparation of either vocal or manual actions.
    1. Neuroscience

    An Information-Theoretic Approach to Reward Rate Optimization in the Tradeoff Between Controlled and Automatic Processing in Neural Network Architectures

    Giovanni Petri, Sebastian Musslick, Jonathan D. Cohen
    Not revised
    Reviewed Preprint v1
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