Ramon A van der Valk, Jocelyne Vreede ... Remus T Dame
The DNA-bridging efficiency of H-NS, a genome organising and transcription regulatory protein, is modulated by changes in environmental conditions of the cell, which drive a structural rearrangement of the protein.
Tensile stress patterns in tissues are revealed by cell-cell adhesion defects; in turn, cell responses to supracellular tension require cell-cell adhesion.
Nils Stührwohldt, Stefan Scholl ... Andreas Schaller
Step-wise processing of plant peptide hormone precursors by subtilisin-like proteinases in consecutive compartments of the secretory pathway is required for formation and secretion of the bioactive peptides.
Benjamin C McIlwain, Roja Gundepudi ... Randy B Stockbridge
In the extremely selective fluoride channels from the bacterial Fluc family, fluoride ions access the pore via two points, an electropositive vestibule and a triad of conserved residues involved in anion recognition.
Emilio Salinas, Benjamin R Steinberg ... Terrence R Stanford
Looking away from a salient visual stimulus pits the reflexive urge to look toward it against the voluntary intention not to, and this conflict is resolved within tens of milliseconds.
Humans and other animals have different strategies for extracting the pitch of sounds, potentially driven by the species-specific frequency selectivity of the ear.
Functional definition of NrtR and the discovery of its acetylation represents a first paradigm for linking protein acetylation to bacterial central NAD+ metabolism.
Maria Podinovskaia, Cristina Prescianotto-Baschong ... Anne Spang
A novel, inexpensive, easy-to-use method to analyse traffic along the endosomal pathway in mammalian cells shows that there is coordination between Rab conversion and acidification, but almost none between Rab conversion and recycling.