Browse the search results

Page 3 of 233
    1. Computational and Systems Biology
    2. Physics of Living Systems

    How microscopic epistasis and clonal interference shape the fitness trajectory in a spin glass model of microbial long-term evolution

    Nicholas M Boffi, Yipei Guo ... Ariel Amir
    High-resolution simulations of evolving microbial populations reveal that microscopic epistasis slows the rate of adaptation, while clonal interference can either speed it up or leave it fixed.
    1. Physics of Living Systems

    Large-scale orientational order in bacterial colonies during inward growth

    Mustafa Basaran, Y Ilker Yaman ... Askin Kocabas
    When crowded bacterial colonies invade a closed area, flow-induced alignment creates strong radial orientation and leads to the formation of aster defects.
    1. Computational and Systems Biology
    2. Neuroscience

    From behavior to circuit modeling of light-seeking navigation in zebrafish larvae

    Sophia Karpenko, Sebastien Wolf ... Georges Debrégeas
    Light-seeking strategies in Zebrafish larvae are dissected using a virtual-reality assay, and these data are used to establish minimal stochastic and neural-circuits models that quantitatively capture this behavior.
    1. Physics of Living Systems

    High-speed motility originates from cooperatively pushing and pulling flagella bundles in bilophotrichous bacteria

    Klaas Bente, Sarah Mohammadinejad ... Damien Faivre
    Bacteria reach swimming speeds of several hundred body lengths per second and change direction in less than 5 ms by using coordinated flagella bundle agitation.
    1. Computational and Systems Biology

    Toward the cellular-scale simulation of motor-driven cytoskeletal assemblies

    Wen Yan, Saad Ansari ... Michael Shelley
    aLENS implements new parallel methods to resolve cytoskeletal assembly dynamics with high stability, physical consistency, and scalability.
    1. Physics of Living Systems

    Generating active T1 transitions through mechanochemical feedback

    Rastko Sknepnek, Ilyas Djafer-Cherif ... Silke Henkes
    Directed mechanical stresses can trigger active T1 events that lead to tissue elongation perpendicular to the main direction of tissue stress.
    1. Neuroscience

    Expansion and contraction of resource allocation in sensory bottlenecks

    Laura R Edmondson, Alejandro Jiménez Rodríguez, Hannes P Saal
    A simple efficient coding model predicts complex trade-offs in resource allocation for sensory inputs with heterogeneous receptor densities and activation levels.
    1. Physics of Living Systems

    Origin and role of the cerebrospinal fluid bidirectional flow in the central canal

    Olivier Thouvenin, Ludovic Keiser ... Claire Wyart
    The combination of data and modelling shows the mechanisms underlying bidirectional flow of cerebrospinal fluid and its impact on long range transport in the CSF between brain and spinal cord.
    1. Physics of Living Systems

    Spatial control of neuronal metabolism through glucose-mediated mitochondrial transport regulation

    Anamika Agrawal, Gulcin Pekkurnaz, Elena F Koslover
    A quantitative analysis of glucose-dependent transport regulation indicates that mitochondrial accumulation in regions of high nutrient availability can enhance metabolism in neuronal axons under physiologically relevant conditions.
    1. Physics of Living Systems

    Confinement discerns swarmers from planktonic bacteria

    Weijie Chen, Neha Mani ... Jay X Tang
    For the same bacterial strain, the swarming phenotype can be biophysically discerned from swimming phenotype based on the motion pattern under circular confinement on a soft agar.