809 results found
    1. Ecology

    Experimental and observational studies find contrasting responses of soil nutrients to climate change

    ZY Yuan et al.
    Experimental manipulations and environmental gradients, the two common-used approaches, are not at all comparable for predicting the impacts of climate change on nutrient cycling.
    1. Cell Biology
    2. Developmental Biology

    Nutrient restriction enhances the proliferative potential of cells lacking the tumor suppressor PTEN in mitotic tissues

    Katarzyna Nowak et al.
    Nutrient limitation elicits differential responses in cells lacking the tumor suppressor PTEN and in normal cells, resulting in hyperplastic overgrowth of PTEN mutant tissue independent of additional mutations.
    1. Cell Biology

    The yeast H+-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 activation in response to H+-coupled nutrient uptake

    Elie Saliba et al.
    The H+ influx coupled to nutrient uptake and the plasma membrane H+-ATPase are central actors of the activation of target of rapamycin complex 1 (TORC1) in budding yeast Saccharomyces cerevisiae..
    1. Cell Biology
    2. Microbiology and Infectious Disease

    An essential dual-function complex mediates erythrocyte invasion and channel-mediated nutrient uptake in malaria parasites

    Daisuke Ito et al.
    Gene knockdowns reveal that the conserved RhopH protein complex functions in both host cell invasion and channel-mediated nutrient uptake in malaria.
    1. Cell Biology

    α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism

    Amin Khalifeh-Soltani et al.
    The milk protein Mfge8 promotes fat uptake and slows gastrointestinal motility to optimize nutrient absorption.
    1. Human Biology and Medicine
    2. Neuroscience

    Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar

    Ana I Domingos et al.
    Natural sugars are preferred over artificial sweeteners because of their nutritional content, which is sensed by MCH neurons in the lateral hypothalamus.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

    Natalie A Counihan et al.
    Plasmodium parasites secrete RhopH2 from the rhoptry organelle into their host red blood cell to facilitate the uptake of essential nutrients required for parasite replication and survival.
    1. Biochemistry and Chemical Biology
    2. Human Biology and Medicine

    GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients

    Xuchen Hu et al.
    The expression of the lipoprotein lipase (LPL) transporter GPIHBP1 in glioma capillaries promotes the LPL-mediated processing of triglyceride-rich lipoproteins, thereby providing lipid nutrients for glioma cells.
    1. Neuroscience

    Internal states drive nutrient homeostasis by modulating exploration-exploitation trade-off

    Verónica María Corrales-Carvajal et al.
    A quantitative video tracking analysis reveals that to gain the nutrients they need, flies change their decisions to exploit foods with different nutrient contents and explore the environment according to their internal amino acid and reproductive states.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability

    Mark R Sullivan et al.
    The nutrients available in some tumors and the factors that influence tumor nutrient availability are characterized, which provides insight into the metabolic constraints of the tumor microenvironment.

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