Metabolic cues enlist ubiquitin ligase adaptors for the selective control of cellular nutrient acquisition strategies.

Infection with Mycobacterium tuberculosis triggers de novo synthesis of polyunsaturated fatty acids by host macrophages, which promote their antimicrobial responses but feed the intracellular pathogen.

An ECF-type transporter serves as broad-spectrum heme iron scavenger and allows an opportunistic pathogen to use multiple eukaryotic hemoproteins to overcome nutritional iron-limitation.

An unrecognized regulation on MAGEA protein stability promotes pancreatic cancer progression via manipulating autophagy and may impact the clinical utility of MAGEA-targeted immunotherapy.

Staphylococcal heme acquisition needs a highly structured cell envelope, the membrane transporter accumulates in membrane domains most likely to allow concerted passage of heme from the cell wall-funnel to the membrane.

Cdc5-dependent SPB regulation is linked to delayed cytoplasmic microtubule organization in Ogataea polymorpha.

In the context of an organism's ecology, physiology, and macroevolutionary history, inheritance and gene loss can yield emergent patterns of trait variability that give the appearance of gene acquisition.

Fetus and trophoblast interplay to regulate fetal nutrient supply and, ultimately, affect healthy growth.

An open-source python package for phenotype analyses provides a versatile, modular and user-friendly solution to determine complementary fitness-related traits from large-scale assays of microbial colonies.

Diffusion of differently sized proteins in bacterial cytoplasm is nearly Brownian and consistent with the Stokes-Einstein relation, once protein shape and cell geometry are taken into account, and effects of various perturbation can be described as changes in cytoplasmic viscosity.