Browse the search results

Page 3 of 108
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias

    Bradford M Stubenhaus, John P Dustin ... Jason Pellettieri
    Physiological porphyrin biosynthesis causes photosensitivity in fasted planarians, providing an experimentally tractable animal model of acute porphyrias.
    1. Cell Biology

    α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism

    Amin Khalifeh-Soltani, Arnold Ha ... Kamran Atabai
    The milk protein Mfge8 promotes fat uptake and slows gastrointestinal motility to optimize nutrient absorption.
    1. Cell Biology
    2. Developmental Biology

    Nutrient restriction enhances the proliferative potential of cells lacking the tumor suppressor PTEN in mitotic tissues

    Katarzyna Nowak, Gerhard Seisenbacher ... Hugo Stocker
    Nutrient limitation elicits differential responses in cells lacking the tumor suppressor PTEN and in normal cells, resulting in hyperplastic overgrowth of PTEN mutant tissue independent of additional mutations.
    1. Ecology
    2. Physics of Living Systems

    Nutrient levels and trade-offs control diversity in a serial dilution ecosystem

    Amir Erez, Jaime G Lopez ... Ned S Wingreen
    Whereas theories of ecological diversity mostly consider continuously supplied nutrients, a seasonal model uncovers a general mechanism that controls diversity and reconciles conflicting experimental findings.
    1. Physics of Living Systems

    Spontaneous body wall contractions stabilize the fluid microenvironment that shapes host–microbe associations

    Janna C Nawroth, Christoph Giez ... Thomas CG Bosch
    Spontaneous contractions allow shedding of the fluid boundary layer and thereby stabilize microbiota.
    1. Developmental Biology

    Amino acid transporter SLC38A5 regulates developmental and pathological retinal angiogenesis

    Zhongxiao Wang, Felix Yemanyi ... Jing Chen
    Experimental analysis of SLC38A5 (solute carrier family 38 member 5) in mouse models and cell culture reveals its novel role as a metabolic regulator of retinal angiogenesis by controlling nutrient uptake and homeostasis in blood vessel endothelium.
    1. Ecology

    Multistability and regime shifts in microbial communities explained by competition for essential nutrients

    Veronika Dubinkina, Yulia Fridman ... Sergei Maslov
    Multistability and regime shifts are common and species diversity is high in microbial communities when nutrient supplies are balanced and competing species have different stoichiometries of essential nutrients.
    1. Developmental Biology

    A vitamin-B2-sensing mechanism that regulates gut protease activity to impact animal’s food behavior and growth

    Bin Qi, Marina Kniazeva, Min Han
    The availability of an essential dietary micronutrient is evaluated by an intestinal signaling system that in turn regulates food-uptake and response behaviors by modulating protease expression.
    1. Evolutionary Biology

    Evolution of diversity in metabolic strategies

    Rodrigo Caetano, Yaroslav Ispolatov, Michael Doebeli
    Analytical and numerical analyses reveal that the number of coexisting species exceeds the number of resource only for the structurally unstable case of linear tradeoff.
    1. Neuroscience

    Internal states drive nutrient homeostasis by modulating exploration-exploitation trade-off

    Verónica María Corrales-Carvajal, Aldo A Faisal, Carlos Ribeiro
    A quantitative video tracking analysis reveals that to gain the nutrients they need, flies change their decisions to exploit foods with different nutrient contents and explore the environment according to their internal amino acid and reproductive states.