230 results found
    1. Computational and Systems Biology
    2. Ecology

    Tree crickets optimize the acoustics of baffles to exaggerate their mate-attraction signal

    Natasha Mhatre et al.
    Tree crickets can optimize the baffles they make to increase call loudness without any progressive optimization, and manufacture an optimal baffle in a single attempt, by using a simple yet highly accurate heuristic.
    1. Ecology
    2. Human Biology and Medicine

    Point of View: A transatlantic perspective on 20 emerging issues in biological engineering

    Bonnie C Wintle et al.
    Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.
    1. Developmental Biology and Stem Cells
    2. Neuroscience

    Microscopy: Imaging far and wide

    Raghav K Chhetri, Philipp J Keller
    Insight
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    1. Genes and Chromosomes

    Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe

    Rajesh K Yadav et al.
    Mutation of Glycine 34 to Arginine within the N-terminal tail of histone H3 alters post-translational modifications on Lysine 36 and is associated with a delay in replication restart, defective homologous recombination and an increase in genomic instability.
    1. Cell Biology

    The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms

    Wenbao Hu et al.
    XIAP/TRIP-Br1-mediated degradation of multiple adenylyl cyclase isoforms is a previously unrecognised general mechanism for controlling adenylyl cyclase expression and the homeostasis of cAMP signalling.
    1. Ecology

    Sequestration and activation of plant toxins protect the western corn rootworm from enemies at multiple trophic levels

    Christelle AM Robert et al.
    The western corn rootworm escapes biological control by entomopathogenic nematodes by partitioning and phenocopying the plant defense system for self-protection.
    1. Neuroscience

    Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons

    Daniel J Galtieri et al.
    Pedunculopontine neurons can evoke burst spiking in substantia nigra dopaminergic neurons without engaging a subtype of glutamate receptor previously thought to be necessary for this spiking mode.
    1. Cancer Biology

    Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer

    Kevin M Elias et al.
    Application of machine learning to serum miRNA profiles generated through next generation sequencing identifies a biologically relevant miRNA signature which can be deployed as a qPCR test to assist the diagnosis of epithelial ovarian cancer.
    1. Genomics and Evolutionary Biology

    Homo naledi and Pleistocene hominin evolution in subequatorial Africa

    Lee R Berger et al.
    A late Middle Pleistocene age for Homo naledi demonstrates a diversity of hominin species in Africa at this critical time in the archaeological record.
    1. Neuroscience

    Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice

    Claudia Villani et al.
    Lovastatin ability to rescue motor deficits and survival in a mouse model of Rett syndrome is strongly influenced by the genetic background.

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