159 results found
    1. Neuroscience

    Sex differences in discrimination behavior and orbitofrontal engagement during context-gated reward prediction

    Sophie Peterson, Amanda Maheras ... Ronald Keiflin
    Rodent model of context-dependent discrimination reveals sex-biased tradeoff between speed of acquisition and robustness of contextual control over cue-elicited reward seeking, linked to orbitofrontal cortex activation.
    1. Neuroscience

    Discriminative stimuli are sufficient for incubation of cocaine craving

    Rajtarun Madangopal, Brendan J Tunstall ... Bruce T Hope
    Stimuli signaling reward availability potentiate and control relapse for up to 300 days of abstinence following cocaine, but not food, self-administration in rats.
    1. Neuroscience

    Spatial tuning and brain state account for dorsal hippocampal CA1 activity in a non-spatial learning task

    Kevin Q Shan, Evgueniy V Lubenov ... Athanassios G Siapas
    Recordings in freely-moving rats show that hippocampal dorsal CA1 pyramidal cells signal only spatial information, even in a non-spatial task such as trace eyeblink conditioning.
    1. Neuroscience

    Assessing reliability in neuroimaging research through intra-class effect decomposition (ICED)

    Andreas M Brandmaier, Elisabeth Wenger ... Ulman Lindenberger
    In human neuroimaging, the intra-class effect decomposition (ICED) framework indexes overall reliability, and enables researchers to identify and quantify multi-source contributions to measurement error with the goal of developing more reliable measures.
    1. Neuroscience

    Offline replay supports planning in human reinforcement learning

    Ida Momennejad, A Ross Otto ... Kenneth A Norman
    fMRI evidence for off-task replay predicts subsequent replanning behavior in humans, suggesting that learning from simulated experience during replay helps update past policies in reinforcement learning.
    1. Computational and Systems Biology
    2. Neuroscience

    Evolving interpretable plasticity for spiking networks

    Jakob Jordan, Maximilian Schmidt ... Mihai A Petrovici
    Artificial evolution discovers biophysically plausible plasticity rules for spiking networks that perform competitively with and even outperform labor-intensive human-designed models in various learning scenarios, while providing new views on experimental data.
    1. Ecology

    Tropical land use alters functional diversity of soil food webs and leads to monopolization of the detrital energy channel

    Zheng Zhou, Valentyna Krashevska ... Anton Potapov
    Tropical land use makes most soil animal groups shift to 'fast' energy channel and restructures soil food web at community level, but this change is buffered by earthworms at ecosystem (energetic) level.
    1. Immunology and Inflammation

    Circulating T cell-monocyte complexes are markers of immune perturbations

    Julie G Burel, Mikhail Pomaznoy ... Bjoern Peters
    Human blood contains T cell-monocyte complexes which are not technical artefacts but reflect true in vivo immune cell interactions.
  1. Graphic design visual of a tangled web being untangled into code data and environment

    Gigantum – a simple way to create and share reproducible data science and research

    Gigantum is an open data science platform that bundles fully versioned data, code and environment, letting anybody work locally but share globally with a single click.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus

    Ryan S Wible, Chidambaram Ramanathan ... Thomas R Sutter
    NRF2 is the mechanism through which oxidative signals directly input into the circadian clockwork to link metabolism and timekeeping in Mus musculus.

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