326 results found
    1. Neuroscience

    Slow presynaptic mechanisms that mediate adaptation in the olfactory pathway of Drosophila

    Carlotta Martelli, André Fiala
    Slow presynaptic depression in olfactory receptor neurons rescales combinatorial odor representations in postsynaptic neurons and mediates the encoding of stimulus mean and variance.
    1. Neuroscience

    Local synaptic inputs support opposing, network-specific odor representations in a widely projecting modulatory neuron

    Xiaonan Zhang et al.
    The activity of serotonergic neurons spanning multiple olfactory areas is regulated by both local synaptic interactions and dendrite wide computations.
    1. Neuroscience

    NMDA spikes mediate amplification of inputs in the rat piriform cortex

    Amit Kumar et al.
    Dendrites of pyramidal neurons in piriform cortex can initiate NMDA spikes, which may serve to amplify odor responses, and provide combination selectivity underlying 'discontinuous' odor receptive fields in these neurons.
    1. Neuroscience

    A transformation from temporal to ensemble coding in a model of piriform cortex

    Merav Stern et al.
    A spiking network model that examines the transformation of odor information from olfactory bulb to piriform cortex demonstrates how intrinsic cortical circuitry preserves representations of odor identity across odorant concentrations.
    1. Computational and Systems Biology
    2. Neuroscience

    Front-end Weber-Fechner gain control enhances the fidelity of combinatorial odor coding

    Nirag Kadakia, Thierry Emonet
    In multi-channel sensory systems, gain adaptation can help maintain not only coding capacity across changes in signal intensity, but also combinatorial representations of odor identity.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM: Protein complexes in focus

    Robert M Glaeser
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    1. Neuroscience

    Memory Formation: Let’s replay

    Björn Rasch
    Reactivating brain activity patterns during sleep enhances memory performance the next day.
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    1. Neuroscience

    Associative Memory: A big picture of a small brain

    Leslie C Griffith
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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: Viral factors in influenza pandemic risk assessment

    Marc Lipsitch et al.
    We identify key strengths and limitations in use of viral genotyping and phenotyping to estimate pandemic risk from influenza A viruses, focusing on 3 traits, hemagglutinin binding specificity, hemagglutinin pH of activation, and polymerase complex efficiency.
    1. Neuroscience

    Neuroscience: How keeping active pays off in the olfactory system

    Kevin Monahan, Stavros Lomvardas
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