356 results found
    1. Chromosomes and Gene Expression

    Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

    Kevin Monahan et al.
    Biochemical and genetic experiments show that Ebf and Lhx2 cooperate to specify olfactory receptor enhancers, which cooperate to drive olfactory receptor expression.
    1. Developmental Biology

    Cell-type heterogeneity in the early zebrafish olfactory epithelium is generated from progenitors within preplacodal ectoderm

    Raphaël Aguillon et al.
    Several neuronal subtypes found in the early zebrafish olfactory placode are not derived from the neural crest, as previously thought, but from the preplacodal ectoderm.
    1. Genetics and Genomics
    2. Neuroscience

    Variation in olfactory neuron repertoires is genetically controlled and environmentally modulated

    Ximena Ibarra-Soria et al.
    The neuronal composition of a mouse’s nose is individually unique due to a combination of olfactory experience and genetic variation local to olfactory receptor genes.
    1. Neuroscience

    Opposite regulation of inhibition by adult-born granule cells during implicit versus explicit olfactory learning

    Nathalie Mandairon et al.
    While both implicit and explicit learning augment neurogenesis, adult-born cells differ in their morphology, functional coupling and inhibitory action impacting differentially the olfactory bulb output.
    1. Neuroscience

    Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

    Wankun L Li et al.
    Adult-born neurons in the olfactory bulb allow state-dependent pattern separation of representations of similar odorants.
    1. Neuroscience

    Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey

    Yen-Ping Hsueh et al.
    Genetic and behavior analyses show that Caenorhabditis nematodes are lured to the predator Arthrobotrys oligospora by olfactory mimicry of food and sex cues.
    1. Neuroscience

    Massive normalization of olfactory bulb output in mice with a 'monoclonal nose'

    Benjamin Roland et al.
    Inhibitory circuits in the olfactory bulb can amplify or suppress sensory inputs over a wide range of intensities to generate robust mitral cell output.
    1. Neuroscience

    The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb

    Ronen Reshef et al.
    During adult neurogenesis in the olfactory bulb, microglia regulate the elimination (pruning), formation, and maintenance of synapses on newborn neurons, contributing to the functional integrity of the olfactory bulb circuitry.
    1. Evolutionary Biology

    Evolution of insect olfactory receptors

    Christine Missbach et al.
    Insect specific olfactory receptors are not an adaptation to a terrestrial insect lifestyle, but evolved later in insect evolution.
    1. Neuroscience

    The activity-dependent histone variant H2BE modulates the life span of olfactory neurons

    Stephen W Santoro, Catherine Dulac
    A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.

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