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510 results found
    1. Neuroscience

    Microglial depletion disrupts normal functional development of adult-born neurons in the olfactory bulb

    Jenelle Wallace et al.
    Adult-born neurons in the olfactory bulb that develop in the absence of microglia have a higher density of small spines but weaker excitatory inputs and reduced responses to sensory stimuli.
    1. Neuroscience

    Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons

    Qijing Xie et al.
    Single-cell transcriptomes of Drosophila olfactory projection neurons correspond to previously defined cell types, exhibit unique characteristics at different developmental stages, and reveal cell-type-specific gene expression programs in development and function.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Developmental programming modulates olfactory behavior in C. elegans via endogenous RNAi pathways

    Jennie R Sims et al.
    The OSM-9 TRPV channel is differentially regulated due to developmental programming via modulation by TGF-β signaling, endogenous RNAi and chromatin remodeling pathways.
    1. Neuroscience

    Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron

    Elisa Galliano et al.
    In the mouse olfactory bulb, different types of local dopaminergic interneuron are produced before and after birth.
    1. Developmental Biology

    Axon tension regulates fasciculation/defasciculation through the control of axon shaft zippering

    Daniel Šmít et al.
    Competition between adhesive and tensile forces regulates axon fasciculation, thus introducing a new role of mechanical tension in the development of neural networks.
    1. Developmental Biology
    2. Neuroscience

    Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish

    Ankur Saxena et al.
    Sensory neurons in the olfactory system develop from two different regions of the ectoderm, the olfactory placode and the cranial neural crest, whereas sensory neurons within the eye and ear develop from just one region.
    1. Developmental Biology
    2. Neuroscience

    Presynaptic developmental plasticity allows robust sparse wiring of the Drosophila mushroom body

    Najia A Elkahlah et al.
    Sensory innervation density in the insect associative learning center is set by postsynaptic cells and accomplished by flexible allocation of processes by presynaptic cells.
    1. Neuroscience

    Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila

    Colleen N McLaughlin et al.
    Single-cell transcriptomes of olfactory receptor neurons at multiple developmental stages reveal cell-type-specific gene expression programs that underlie their development and sensory biology.
    1. Developmental Biology
    2. Neuroscience

    Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring, and functional determinants

    J Roman Arguello et al.
    Targeted expression of molecular probes for gene expression and chromatin accessibility in subpopulations of neurons in the Drosophila olfactory system identifies genes required for their development and function.
    1. Developmental Biology
    2. Neuroscience

    The role of the NMD factor UPF3B in olfactory sensory neurons

    Kun Tan et al.
    The nonsense-mediated RNA decay (NMD) branch-specific factor UPF3B influences olfactory sensory neuron cell populations, the olfactory receptor repertoire, and antimicrobial gene expression.

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