Sister projection neurons in the mammalian olfactory system do not share sensory synaptic input indicating that lineage-independent mechanisms regulate their synaptic connectivity with the olfactory sensory neurons.
Sensory neurons in the olfactory system develop from two different regions of the ectoderm, the olfactory placode and the cranial neural crest, whereas sensory neurons within the eye and ear develop from just one region.
J Roman Arguello, Liliane Abuin ... Richard Benton
Targeted expression of molecular probes for gene expression and chromatin accessibility in subpopulations of neurons in the Drosophila olfactory system identifies genes required for their development and function.
Combinatorial expression patterns of δ-Pcdhs are defined within single neurons, and in vitro assays are employed to establish guiding principles used by this gene family to mediate cell adhesion.
FlyBrainLab is an open-source computing platform that integrates 3D exploration and visualization of diverse Drosophila connectomic/synaptomic datasets with interactive exploration of the functional logic of modeled executable brain circuits.
Aljoscha Schulze, Alex Gomez-Marin ... Matthieu Louis
A computational model for the control of chemotaxis in the Drosophila larva clarifies the link between the peripheral encoding of naturalistic olfactory stimuli and action selection.
Neurons in the fruit fly olfactory system respond most strongly to the sudden appearance of an odor, and to odors that are changing rapidly in strength, but are relatively insensitive to the absolute levels of an odor.
Benjamin Roland, Rebecca Jordan ... Alexander Fleischmann
Inhibitory circuits in the olfactory bulb can amplify or suppress sensory inputs over a wide range of intensities to generate robust mitral cell output.
