Human primary olfactory cortical regions can be parcellated into anatomically distinct areas based on whole-brain functional connectivity profiles, suggesting distinct, parallel functional pathways in the human olfactory system.
Vax1 suppresses dopaminergic neuron phenotype by inhibiting Pax6 expression in the subventricular zone of the lateral ventricle and is necessary to generate Calbindin interneurons for the postnatal olfactory bulb.
Sensory neurons in the olfactory system develop from two different regions of the ectoderm, the olfactory placode and the cranial neural crest, whereas sensory neurons within the eye and ear develop from just one region.
In multi-channel sensory systems, gain adaptation can help maintain not only coding capacity across changes in signal intensity, but also combinatorial representations of odor identity.
Drosophila genetics and behavior reveal that oxidative stress induced axonal degeneration in a single class of neurons drives the functional decline of an entire neural network and the behavior it controls.
Sister projection neurons in the mammalian olfactory system do not share sensory synaptic input indicating that lineage-independent mechanisms regulate their synaptic connectivity with the olfactory sensory neurons.
Phototaxis and courtship behavioral preferences reflect strong correlation with differences in olfactory and visual nervous system investment across five monophyletic Drosophila species, and could help explain their speciation events.
