457 results found
    1. Biochemistry and Chemical Biology

    Ctf4 organizes sister replisomes and Pol α into a replication factory

    Zuanning Yuan et al.
    Eukaryotic replisomes are strongly connected together to replicate both sister DNAs produced from a bidirectional origin.
    1. Neuroscience

    The wiring diagram of a glomerular olfactory system

    Matthew E Berck et al.
    The complete neural circuit map of a tractable olfactory system will support studies towards bridging the gap between circuits and behavior.
    1. Computational and Systems Biology
    2. Neuroscience

    Characterizing functional pathways of the human olfactory system

    Guangyu Zhou et al.
    Human primary olfactory cortical regions can be parcellated into anatomically distinct areas based on whole-brain functional connectivity profiles, suggesting distinct, parallel functional pathways in the human olfactory system.
    1. Neuroscience

    Neuroscience: How keeping active pays off in the olfactory system

    Kevin Monahan, Stavros Lomvardas
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    1. Neuroscience

    Cell Communication: Studying gap junctions with PARIS

    Daniel R Kick, David J Schulz
    A new genetically encoded system manipulates the pH inside cells to detect whether they are coupled to each other.
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    1. Neuroscience

    PARIS, an optogenetic method for functionally mapping gap junctions

    Ling Wu et al.
    As the first fully genetically encoded method, PARIS allows cell-specific, long-term, repeated measurements of gap junctional coupling with high spatiotemporal resolution, facilitating its study in both health and disease.
    1. Computational and Systems Biology
    2. Neuroscience

    Front-end Weber-Fechner gain control enhances the fidelity of combinatorial odor coding

    Nirag Kadakia, Thierry Emonet
    In multi-channel sensory systems, gain adaptation can help maintain not only coding capacity across changes in signal intensity, but also combinatorial representations of odor identity.
    1. Neuroscience

    Different types of theta rhythmicity are induced by social and fearful stimuli in a network associated with social memory

    Alex Tendler, Shlomo Wagner
    Variations in the frequency of theta brain waves enable a single network of brain regions to generate appropriate responses to stimuli with different kinds of emotional value.
    1. Neuroscience

    Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in Drosophila

    Ashiq Hussain et al.
    Drosophila genetics and behavior reveal that oxidative stress induced axonal degeneration in a single class of neurons drives the functional decline of an entire neural network and the behavior it controls.
    1. Neuroscience

    Calcium dynamics regulating the timing of decision-making in C. elegans

    Yuki Tanimoto et al.
    A series of quantitative behavioural and opto-physiological analyses using a novel robot microscope system reveals that C. elegans computes the time-differential and time-integral of sensory information for decision-making during olfactory navigation.

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