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    1. Immunology and Inflammation

    Tight nuclear tethering of cGAS is essential for preventing autoreactivity

    Hannah E Volkman et al.
    Tight nuclear tethering of the cGAS DNA sensor maintains it in its resting state and prevents activation by self-DNA.
    1. Cell Biology
    2. Human Biology and Medicine

    Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity

    Rachel A Battaglia et al.
    GFAP protein carries a distinct post-translational modification signature that facilitates its pathogenic accumulation and aggregation in astrocytes of patients who succumb to Alexander Disease very early in life.
    1. Developmental Biology
    2. Evolutionary Biology

    Resolving homology in the face of shifting germ layer origins: Lessons from a major skull vault boundary

    Camilla S Teng et al.
    Homology of vertebrate skull structures should be based on evolutionary continuity and an appreciation of germ layer origins and inductive signaling in the embryonic head.
    1. Developmental Biology
    2. Neuroscience

    EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development

    Eva Harde et al.
    The internalization of the angiogenic receptor VEGFR2 expressed in neurons is controlled by ephrinB2 and is required for neuronal dendritic arborization, spine morphogenesis and circuitry development in the hippocampus.
    1. Evolutionary Biology
    2. Neuroscience

    A novel lineage of candidate pheromone receptors for sex communication in moths

    Lucie Bastin-Héline et al.
    In moths, male receptors tuned to type I female pheromones may not have a monophyletic origin.
    1. Neuroscience

    Reliability of an interneuron response depends on an integrated sensory state

    May Dobosiewicz et al.
    A pair of interneurons in C. elegans condenses information from multiple sensory neurons into a uniform response, using an AND-gate logic to represent a stimulus with positive valence.
    1. Neuroscience

    Single cell transcriptome atlas of the Drosophila larval brain

    Clarisse Brunet Avalos et al.
    Single-cell transcriptomics identifies cellular composition of the first instar Drosophila brain and the response to starvation.
    1. Ecology

    Biophysical and physiological processes causing oxygen loss from coral reefs

    Cynthia B Silveira et al.
    Coral reef heterotrophic bacteria and fleshy macroalgae cause oxygen loss from reef systems through microbial biomass accumulation and ebullition from algae surfaces.
    1. Immunology and Inflammation
    2. Neuroscience

    Intestinal infection regulates behavior and learning via neuroendocrine signaling

    Jogender Singh, Alejandro Aballay
    Feedback from the intestine during infection can modulate the behavior, learning, and microbial perception of the host.
    1. Neuroscience

    Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in Drosophila color vision circuits

    Kaushiki P Menon et al.
    The survival of Drosophila amacrine neurons is controlled by neurotrophic signaling mediated by interactions between the cell surface protein DIP-γ and its partner Dpr11, which is expressed on presynaptic photoreceptors.