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    1. Neuroscience

    The activity-dependent histone variant H2BE modulates the life span of olfactory neurons

    Stephen W Santoro, Catherine Dulac
    A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.
    1. Neuroscience

    Nostril-specific and structure-based olfactory learning of chiral discrimination in human adults

    Guo Feng, Wen Zhou
    Training-induced perceptual gain in the discrimination between odor enantiomers is nostril-specific and structure-based, indicating that early olfactory processing of the chemical features of unirhinal input remains plastic in human adults.
    1. Neuroscience

    Distinct lateral inhibitory circuits drive parallel processing of sensory information in the mammalian olfactory bulb

    Matthew A Geramita et al.
    Distinct lateral inhibitory circuits affect spiking in olfactory bulb mitral and tufted cells differently, which ultimately allows each cell type to best discriminate between similar odors in separate concentration ranges.
    1. Developmental Biology
    2. Neuroscience

    Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish

    Ankur Saxena et al.
    Sensory neurons in the olfactory system develop from two different regions of the ectoderm, the olfactory placode and the cranial neural crest, whereas sensory neurons within the eye and ear develop from just one region.
    1. Neuroscience

    Rapid task-dependent tuning of the mouse olfactory bulb

    Anzhelika Koldaeva et al.
    Sensory representation in the primary olfactory area is rapidly modulated when mice switch between easy and difficult discrimination tasks, optimising the sensory representation for the task at hand.
    1. Neuroscience

    Stepwise wiring of the Drosophila olfactory map requires specific Plexin B levels

    Jiefu Li et al.
    PlexB plays a multifaceted role in instructing the assembly of the Drosophila olfactory circuit through temporally-regulated expression patterns and expression level-dependent effects.
    1. Neuroscience

    Neuroscience: How keeping active pays off in the olfactory system

    Kevin Monahan, Stavros Lomvardas
    Insight
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    1. Neuroscience

    Activation of the dopaminergic pathway from VTA to the medial olfactory tubercle generates odor-preference and reward

    Zhijian Zhang et al.
    The VTA-mOT DAergic pathway mediates a variety of naturalistic reward processes and different types of preferences including odor-preference.
    1. Neuroscience

    Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in Drosophila

    Ashiq Hussain et al.
    Drosophila genetics and behavior reveal that oxidative stress induced axonal degeneration in a single class of neurons drives the functional decline of an entire neural network and the behavior it controls.