1,930 results found
    1. Chromosomes and Gene Expression

    Translational initiation in E. coli occurs at the correct sites genome-wide in the absence of mRNA-rRNA base-pairing

    Kazuki Saito et al.
    E. coli ribosomes incapable of base-pairing with the Shine-Dalgarno sequence are still selective for annotated start sites, indicating these sites are hard-wired for initiation by other mRNA features.
    1. Neuroscience

    Experience shapes activity dynamics and stimulus coding of VIP inhibitory cells

    Marina Garrett et al.
    VIP inhibitory neurons are active in response to novel images but are suppressed by familiar stimuli and show ramping activity when expected stimuli are omitted.
    1. Neuroscience

    β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery

    Matthew L Rook et al.
    The rotation of the β11-12 linker is a crucial control point for acid-sensing ion channel gating and motion of this linker is required for the channel to desensitize.
    1. Cell Biology

    Control of cell death/survival balance by the MET dependence receptor

    Leslie Duplaquet et al.
    MET acts as a dependence receptor in vivo by promoting hepatocyte apoptosis, a response induced by a caspase generated fragment able to favor calcium exchange between endoplasmic reticulum and mitochondria.
    1. Ecology
    2. Microbiology and Infectious Disease

    Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin

    Maria Cristina Stroe et al.
    A silent gene cluster of the fungus Aspergillus fumigatus is activated by a bacterium and leads to the production of a novel spore germination inhibitor targeting the inducing bacterium.
    1. Cell Biology
    2. Ecology

    Ubiquitous macropinocytosis in anthozoans

    Philippe Ganot et al.
    Macropinocytosis, the process of non-specific endocytosis, is a major gateway for large volumes of surrounding medium and nanoparticles to coral cells.
    1. Neuroscience

    Quantitative properties of a feedback circuit predict frequency-dependent pattern separation

    Oliver Braganza et al.
    The feedback inhibitory microcircuit of the dentate gyrus likely boosts pattern separation during gamma oscillations.
    1. Developmental Biology
    2. Neuroscience

    Presynaptic developmental plasticity allows robust sparse wiring of the Drosophila mushroom body

    Najia A Elkahlah et al.
    Sensory innervation density in the insect associative learning center is set by postsynaptic cells and accomplished by flexible allocation of processes by presynaptic cells.
    1. Biochemistry and Chemical Biology

    Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription

    Sarah K Stumper et al.
    Single-molecule observations reveal a mechanism that may be used by multiple competing regulatory proteins to control ribosomal RNA production during rapid bacterial cell growth.

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