2,628 results found
    1. Neuroscience

    Complementary congruent and opposite neurons achieve concurrent multisensory integration and segregation

    Wen-Hao Zhang et al.
    Opposite neurons in multisensory areas compute the cue disparity information essential for information segregation.
    1. Developmental Biology
    2. Neuroscience

    Extrinsic activin signaling cooperates with an intrinsic temporal program to increase mushroom body neuronal diversity

    Anthony M Rossi, Claude Desplan
    The activin ligand myoglianin acts as a temporal extrinsic cue to regulate the intrinsic temporal factor Imp in mushroom body neuroblasts, increasing neuronal diversity by specifying the α’β’ fate.
    1. Neuroscience

    Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales

    Yael Mandelblat-Cerf et al.
    Gradual changes in the firing of specific hypothalamic neurons over many hours signal falling energy levels, while short-lived changes over seconds and minutes signal the availability of food.
    1. Neuroscience

    Arcuate nucleus and lateral hypothalamic CART neurons in the mouse brain exert opposing effects on energy expenditure

    Aitak Farzi et al.
    CART exerts differential metabolic effects in response to activation of neurons of the Arc, where CART suppresses energy expenditure, while it enforces the reward characteristics of the LHA.
    1. Neuroscience

    Local synaptic inputs support opposing, network-specific odor representations in a widely projecting modulatory neuron

    Xiaonan Zhang et al.
    The activity of serotonergic neurons spanning multiple olfactory areas is regulated by both local synaptic interactions and dendrite wide computations.
    1. Neuroscience

    CD40 is a major regulator of dendrite growth from developing excitatory and inhibitory neurons

    Paulina Carriba, Alun M Davies
    CD40-activated CD40L-mediated reverse signalling has strikingly opposite effects on the growth of excitatory and inhibitory neuron dendrites in the developing brain of mice.
    1. Neuroscience

    A bidirectional network for appetite control in larval zebrafish

    Caroline Lei Wee et al.
    Brain imaging and behavioral analysis reveal two opposing states of hunger, represented by anti-correlated lateral and caudal hypothalamic dynamics that are important for the homeostatic control of feeding in zebrafish.
    1. Neuroscience

    Starvation promotes concerted modulation of appetitive olfactory behavior via parallel neuromodulatory circuits

    Kang I Ko et al.
    Starvation upregulates activity in certain sensory channels and downregulates it in others in what appears to be an optimization strategy that serves to increase the hedonic value of food odors.
    1. Neuroscience

    Regulation of starvation-induced hyperactivity by insulin and glucagon signaling in adult Drosophila

    Yue Yu et al.
    Two functionally antagonizing groups of hormones directly regulate starvation-induced increase in locomotion via a common neural target in fruit flies.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells

    Osama F Harraz et al.
    TRPV4 channels in brain capillaries are suppressed by the phosphoinositide PIP2 and activated by receptor agonists implicated in neurovascular coupling.

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