191 results found
    1. Neuroscience

    Using an achiasmic human visual system to quantify the relationship between the fMRI BOLD signal and neural response

    Pinglei Bao, Christopher J Purington, Bosco S Tjan
    The lower-level retinotopic visual cortex of humans born without the optic chiasm comprises two independent neuronal populations and forms a versatile model for quantifying the relationship between the fMRI BOLD signal and neural response.
    1. Developmental Biology
    2. Neuroscience

    Regulation of retinal axon growth by secreted Vax1 homeodomain protein

    Namsuk Kim, Kwang Wook Min ... Jin Woo Kim
    Secreted Vax1 homeodomain protein supports the development of optic chiasm by directly acting at the retinal ganglion cell axon.
    1. Neuroscience

    Sonic hedgehog-dependent recruitment of GABAergic interneurons into the developing visual thalamus

    Rachana Deven Somaiya, Katelyn Stebbins ... Michael A Fox
    Retinal ganglion cell axons release the morphogen sonic hedgehog which signals through astrocytes to induce the migration of inhibitory interneurons into the developing visual thalamus.
    1. Developmental Biology

    Polyploidy in the adult Drosophila brain

    Shyama Nandakumar, Olga Grushko, Laura A Buttitta
    Terminally differentiated neurons and glia can re-enter the cell cycle to become polyploid in the adult fly brain, to protect cells from DNA damage-associated death.
    1. Neuroscience

    A cellular mechanism for inverse effectiveness in multisensory integration

    Torrey LS Truszkowski, Oscar A Carrillo ... Carlos D Aizenman
    Building on previous work (Felch et al., 2016), it is shown that inverse effectiveness, a central property of multisensory integration, in the optic tectum is mediated by the activation of NMDA-type glutamate receptors, resulting in a response greater than the sum of responses to each individual sensory modality.
    1. Neuroscience

    Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

    Emil Kind, Kit D Longden ... Mathias F Wernet
    The fly connectome reveals dedicated cell types for processing specific kinds of visual information such as color or skylight polarization.
    1. Neuroscience

    Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

    Harshvardhan Gazula, Henry FJ Tregidgo ... Juan E Iglesias
    New open-source software enables, for the first time, extraction of quantitative information from brain dissection photographs that are routinely taken at brain banks for archiving purposes but otherwise not exploited.
    1. Developmental Biology
    2. Physics of Living Systems

    Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain

    Amelia J Thompson, Eva K Pillai ... Kristian Franze
    During embryonic development, tissue stiffness, which provides an important signal to motile cells, changes locally within tens of minutes in a well-controlled manner.
    1. Neuroscience

    Dystroglycan is a scaffold for extracellular axon guidance decisions

    L Bailey Lindenmaier, Nicolas Parmentier ... Kevin M Wright
    Dystroglycan interacts with multiple partners, including the transmembrane receptor Celsr3, to regulate axon tract formation throughout the developing nervous system.
    1. Neuroscience

    Manganese-enhanced magnetic resonance imaging reveals light-induced brain asymmetry in embryo

    Elena Lorenzi, Stefano Tambalo ... Angelo Bifone
    The protocol reported can open the way to investigation of the effects of a variety of sensory stimulations on brain activity in embryo.

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