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Local deep hypothermia combined with hibernation-mimicking cold protection is neuroprotective in a translatable large animal model of traumatic optic neuropathy.

Chronic dysregulation of matrix-metalloproteinase 9, which is associated with some neurodevelopmental disorders, leads to local hyperconnectivity in the developing brain, resulting in altered sensory processing and increased seizure susceptibility.

Extrinsic signals establish an invariant and stereotyped pattern of neuronal differentiation and programmed cell death in the Drosophila visual system.

A complete connectome of the ON and OFF motion pathways of the Drosophila optic lobe is acquired using three-dimensional EM methods, and the similarities and differences of the two pathways are uncovered.

Single-cell transcriptomics identifies cellular composition of the first instar Drosophila brain and the response to starvation.

Hunger-sensitive AgRP neurons must sense changes in calorie availability to transmit metabolic information into dopamine release in the NAc and dorsal striatum, albeit over different time frames, to increase motivated food reward seeking.

A new eye-specific Dcc mutant combined with an improved clearing protocol for the eye and brain (EyeDISCO) reveals the requirement of the receptor Dcc for retinal development and maintenance.

Neuroanatomical studies reveal presence and cholinergic phenotype of 150,000-200,000 extrahypothalamic gonadotropin-releasing hormone neurons in human basal ganglia and basal forebrain, and RNA-sequencing detects gonadotropin-releasing hormone receptor-1 expression in cholinergic interneurons but not in spiny projection neurons of the human putamen.

Digital reconstruction of environment combined with eye and head-tracking enabled the process of prey-detection and capture to be seen from the freely moving mouse’s point-of-view and shows the exact visual-field and retinal location mice use when chasing prey and the advantage.

Neurons called lobula columnar cells help fruit flies respond appropriately to specific visual cues, such as those signaling an approaching predator.