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CELF RNA binding proteins promote axon regeneration in
and mammals through alternative splicing of Syntaxins
Lizhen Chen et al.
Genetics and genomics approaches reveal a conserved post-transcriptional regulatory mechanism that promotes adult axon regeneration from worm to mammals.
Microbiology and Infectious Disease
Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium
David R Hill et al.
Contact with bacteria and subsequent hypoxia promotes functional maturation of the immature gastrointestinal tract.
Two receptor tyrosine phosphatases dictate the depth of axonal stabilizing layer in the visual system
Satoko Hakeda-Suzuki et al.
Two receptor tyrosine phosphatases having overlapping function for the determination of the final axon stabilizing layer is encoded for their cumulative cytoplasmic activity and ligand specificity in the visual system.
uses a tripod gait across all walking speeds, and the geometry of the tripod is important for speed control
Chanwoo Chun et al.
uses a gait close to the tripod throughout its speed range, and changes in speed are accompanied by changes in the geometry of the tripod.
A Bayesian approach to dynamic homology of morphological characters and the ancestral phenotype of jawed vertebrates
Benedict King, Martin Rücklin
The ancestor of all known jawed vertebrates possessed a maxilla and premaxilla and was similar in morphology to the 'maxillate placoderms' from China.
Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy
Peter M LoCoco et al.
Stimulation of the rate-limiting enzyme in the NAD salvage pathway protected against neurotoxicity and subsequent peripheral neuropathy associated with the widely utilized anticancer drug, paclitaxel.
Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system
Gianluca Figlia et al.
High PI3K-Akt-mTORC1 activity inhibits Schwann cell differentiation, while after onset of myelination, residual PI3K-Akt-mTORC1 activity promotes myelin growth.
An excitatory cortical feedback loop gates retinal wave transmission in rodent thalamus
Yasunobu Murata, Matthew T Colonnese
The absence of functional inhibition is a developmentally transient circuit property of corticothalamic feedback that is essential for the central transmission of spontaneous retinal waves.
GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice
Srikanta Chowdhury et al.
Functional identification of GABAergic neurons in the ventral tegmental area as a important neuronal subpopulation regulating non-rapid eye movement (NREM) sleep in mice.
Metal microdrive and head cap system for silicon probe recovery in freely moving rodent
Mihály Vöröslakos et al.
A reusable system of 3D printed stainless steel microdrive and plastic head cap allows stable recording of electrophysiological data in mice and rats and easy recovery of silicon probes.
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