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    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Point of View: Looking back and looking forward at Janelia

    Gerald M Rubin, Erin K O'Shea
    The Janelia Research Campus opened its doors 12 years ago: we describe the philosophy underpinning Janelia, the lessons learned, and plans for the future.
    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: Advancing biology through a deeper understanding of zebrafish ecology and evolution

    David M Parichy
    The zebrafish is a premier model organism for biomedical research, with a rich array of tools and genomic resources, and combining these with a fuller appreciation of wild zebrafish ecology could greatly extend its utility in biological research.
    1. Computational and Systems Biology

    Point of View: Data science for the scientific life cycle

    Daphne Ezer, Kirstie Whitaker
    Each stage of the scientific life cycle stands to benefit from the introduction of data science techniques.
    1. Neuroscience

    Computational Psychiatry: Exploring atypical timescales in the brain

    Leonardo L Gollo
    Identifying activity imbalances in specific brain regions may help to diagnose and treat psychiatric disorders.
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    1. Neuroscience

    Intracortical Microstimulation: Regaining the senses of touch and movement

    Victor de Lafuente
    Artificially activating certain neurons in the cortex can make a tetraplegic patient feel naturalistic sensations of skin pressure and arm movement.
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  1. Research: Publication bias and the canonization of false facts

    Silas Boye Nissen et al.
    Publication bias, in which positive results are preferentially reported by authors and published by journals, can restrict the visibility of evidence against false claims and allow such claims to be canonized inappropriately as facts.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Mechanobiology: A brighter force gauge for cells

    Victor Pui-Yan Ma, Khalid Salaita
    An improved biosensor sheds new light on tension within proteins.
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  2. Peer Review: Decisions, decisions

    Peter Rodgers
    Journals are exploring new approaches to peer review in order to reduce bias, increase transparency and respond to author preferences.
  3. Research: Theory, models and biology

    Wenying Shou et al.
    Theoretical ideas have a rich history in many areas of biology, and new theories and mathematical models have much to offer in the future.
    Editorial
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    1. Plant Biology
    2. Genetics and Genomics

    The Natural History of Model Organisms: Genetic, evolutionary and plant breeding insights from the domestication of maize

    Sarah Hake, Jeffrey Ross-Ibarra
    Comparing maize to its wild ancestor teosinte advances our understanding of how it and other cereal crops evolved, and also identifies the genetic variation that can contribute to important agricultural traits.