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Dopamine neurons drive fear extinction learning by signaling the omission of expected aversive outcomes
Ximena I Salinas-Hernández et al.
Dopamine signaling is necessary for normal fear extinction learning.
Frequency-selective control of cortical and subcortical networks by central thalamus
Jia Liu et al.
Central thalamus relay neurons dynamically switch the activity of cortical and subcortical networks at distinct frequencies, providing a mechanism for this region's role in arousal regulation.
Striatal direct and indirect pathway neurons differentially control the encoding and updating of goal-directed learning
James Peak et al.
Direct and indirect pathway neurons in posterior dorsomedial striatum were found to play distinct roles, with the former necessary for encoding and the latter for updating goal-directed learning.
Performance in even a simple perceptual task depends on mouse secondary visual areas
Hannah C Goldbach et al.
In a simple visual task, that in principle could be performed using information in V1 alone, perturbations of secondary visual areas impair perception.
Keratinocytes contribute to normal cold and heat sensation
Katelyn E Sadler et al.
Purinergic keratinocyte-to-sensory neuron signaling is a ubiquitous amplification mechanism that is required for normal mechanical, cold, and heat sensation in vivo.
Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times
Lili X Cai et al.
Dopamine neurons in medial versus lateral VTA encode different signals during fear extinction, yet inhibition of both populations influences fear extinction, at different times.
Cerebellar Purkinje cell activity modulates aggressive behavior
Skyler L Jackman et al.
Optogenetic control of Purkinje cells in the cerebellar vermis enables bidirectional control of aggression.
Optogenetic feedback control of neural activity
Jonathan P Newman et al.
The 'Optoclamp' is a feedback control technology that enables precise, continuously updated, closed-loop optical control of neural firing both in vitro and in vivo.
Dorsal raphe nucleus to anterior cingulate cortex 5-HTergic neural circuit modulates consolation and sociability
Laifu Li et al.
Inhibition of 5-HT neurons in the dorsal raphe nuclei or 5-HT terminals in the anterior cingulate cortex decreased consolation-like behaviors and reduced sociability.
Entorhinal-retrosplenial circuits for allocentric-egocentric transformation of boundary coding
Joeri BG van Wijngaarden et al.
An extended border coding circuit across the entorhinal and retrosplenial cortex incorporates self-referenced and viewpoint-invariant boundary information to guide navigation behavior.
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