879 results found
  1. Ion channels: A Collection of Articles

    Edited by Kenton J Swartz et al.
    eLife has published papers on topics related to the molecular structure and functional mechanisms of a diverse array of ion channel proteins.
    1. Chromosomes and Gene Expression
    2. Cell Biology

    Aging, Geroscience and Longevity: A Special Issue

    Edited by Matt Kaeberlein et al.
    eLife is pleased to present a Special Issue to highlight recent advances in the mechanistic understanding of aging and interventions that extend longevity.
    1. Stem Cells and Regenerative Medicine

    CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating Drosophila imaginal discs

    Melanie I Worley et al.
    The CtBP protein stabilizes cell fates in regenerating tissue.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes

    Sridhar Selvaraj et al.
    Treatment of human pluripotent stem cell-derived myotubes with a cocktail of small molecules induces their maturation, as shown by gene expression, biochemical and functional assays.
    1. Plant Biology

    LEAFY maintains apical stem cell activity during shoot development in the fern Ceratopteris richardii 

    Andrew RG Plackett et al.
    Transgenic analysis reveals a role for LEAFY in ferns that supports a trajectory from general to floral meristem-specific function as land plants evolved.
    1. Stem Cells and Regenerative Medicine

    Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors

    In Young Choi et al.
    Using multiple genetic reporter system in human pluripotent stem cells, a transcriptional database for human early myogenesis has been established.
  2. Food for thought: an interview with Ana Domingos

    Ana Domingos of the Gulbenkian Science Institute in Portugal has forged a career learning why we like certain types of food. By looking at the reward system of the mouse brain, she has revealed pathways that explain why animals prefer sugar, and perhaps why it may factor so strongly in the Western diet.
  3. Annual Report: 2018 in review

    We reflect on eLife’s achievements in continuing to improve peer review, transforming technology for academic publishing, and supporting communities for open science.
  4. Illustrating science: an interview with Leslee Lazar

    Neuroscientist Leslee Lazar has always been interested in design and art. Now, as a freelance graphic designer, he creates visual aids that communicate complex scientific information – especially biomedical research – to the right audience.
  5. Repeating the message: an interview with Yunsheng Cheng

    Yunsheng Cheng grew up in a village in Anhui Province in China and received his bachelor's degree from Anhui Normal University. He is currently a graduate student at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, where he studies how neurons transmit signals to other cells. He enjoys listening to country music, and after he graduates he would like to pursue postdoctoral training abroad.

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