125 results found
    1. Neuroscience

    Lateral orbitofrontal cortex promotes trial-by-trial learning of risky, but not spatial, biases

    Christine M Constantinople et al.
    The lateral orbitofrontal cortex promotes learning of abstract, task-specific biases, but not spatial ones.
    1. Neuroscience

    Medial orbitofrontal inactivation does not affect economic choice

    Matthew PH Gardner et al.
    Inactivation of the medial orbitofrontal cortex using an optogenetic approach did not affect behavior in rats on an iconic economic choice task.
    1. Neuroscience

    Orbitofrontal neurons signal sensory associations underlying model-based inference in a sensory preconditioning task

    Brian F Sadacca et al.
    Neural activity in the orbitofrontal cortex (OFC) represents incidental stimulus-stimulus associations, providing additional evidence for OFC having a role in cognition beyond functions centered on processing value or biological significance.
    1. Neuroscience

    Orbitofrontal neurons acquire responses to ‘valueless’ Pavlovian cues during unblocking

    Michael A McDannald et al.
    Orbitofrontal cortex neurons fire in response to cues with no value independent of what can be inferred through features of the predicted outcome.
    1. Neuroscience

    Responding to preconditioned cues is devaluation sensitive and requires orbitofrontal cortex during cue-cue learning

    Evan E Hart et al.
    The orbitofrontal cortex is necessary for learning about value-neutral sensory associations to impact subsequent model-based behavior.
    1. Neuroscience

    Functional heterogeneity within the rodent lateral orbitofrontal cortex dissociates outcome devaluation and reversal learning deficits

    Marios C Panayi, Simon Killcross
    The rodent orbitofrontal cortex makes functionally distinct contributions to flexible behavioural control, even within a single putative orbitofrontal subregion, which has important implications for establishing homology between rodent and primate orbitofrontal cortex.
    1. Neuroscience

    Covert shift of attention modulates the value encoding in the orbitofrontal cortex

    Yang Xie et al.
    The orbitofrontal neurons only encode the value of one item, which may be selected by covert attention combining factors of value and visual salience, suggesting a sequential processing mechanism of value information in the brain.
    1. Neuroscience

    Instructed knowledge shapes feedback-driven aversive learning in striatum and orbitofrontal cortex, but not the amygdala

    Lauren Y Atlas et al.
    While the striatum and orbitofrontal cortex learn about threats through verbal warnings, the amygdala learns only from direct experience, suggesting that the amygdala forms part of a specialized threat detection system.
    1. Neuroscience

    Lateral orbitofrontal neurons acquire responses to upshifted, downshifted, or blocked cues during unblocking

    Nina Lopatina et al.
    Building on previous work (McDannald et. al, 2014), it is shown that dissociable populations of neurons in the lateral orbitofrontal cortex acquire responses to cues that predict more, less, or no change in reward in rats during training in a Pavlovian unblocking task.
    1. Neuroscience

    Specialized areas for value updating and goal selection in the primate orbitofrontal cortex

    Elisabeth A Murray et al.
    Within the monkey orbitofrontal cortex, a posterior part learns new values, whereas an anterior part translates this knowledge into advantageous decisions.

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