20 results found
    1. Neuroscience

    Dual orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy

    Chi Jung Hung et al.
    New transgenic mice, which can be ablated both orexin neurons and MCH neurons, showed new brain state and revealed functional interaction that MCH neurons have protective role in narcolepsy symptoms.
    1. Neuroscience

    Hypocretin neuron-specific transcriptome profiling identifies the sleep modulator Kcnh4a

    Laura Yelin-Bekerman et al.
    Comprehensive gene profiling of the hypothalamic hypocretin neurons, high resolution imaging and behavioral assays have revealed the molecular signature of these versatile neurons and identified a potassium channel that is required for nighttime sleep.
    1. Neuroscience

    GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice

    Srikanta Chowdhury et al.
    Functional identification of GABAergic neurons in the ventral tegmental area as a important neuronal subpopulation regulating non-rapid eye movement (NREM) sleep in mice.
    1. Neuroscience

    Hypocretin underlies the evolution of sleep loss in the Mexican cavefish

    James B Jaggard et al.
    The identification of evolutionarily-derived changes in Hypocretin function within the brains of short-sleeping Mexican cavefish provides a system for investigating the mechanistic basis of sleep differences throughout the animal kingdom.
    1. Neuroscience

    Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice

    Srikanta Chowdhury et al.
    Subtraction analysis using novel Orexin-Flp mice isolated physiological importance of orexin peptides.
    1. Neuroscience

    A bidirectional network for appetite control in larval zebrafish

    Caroline Lei Wee et al.
    Brain imaging and behavioral analysis reveal two opposing states of hunger, represented by anti-correlated lateral and caudal hypothalamic dynamics that are important for the homeostatic control of feeding in zebrafish.
    1. Neuroscience

    Transcriptomics: Resting easy with a sleep regulator

    William J Giardino, Luis de Lecea
    Insight
    Available as:
    • HTML
    • PDF
    1. Neuroscience

    Obesity: The emerging neurobiology of calorie addiction

    Cristina García-Cáceres, Matthias H Tschöp
    Insight
    Available as:
    • HTML
    • PDF
    1. Genetics and Genomics
    2. Neuroscience

    A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

    Benjamin W Okaty et al.
    Dorsal raphe Pet1 neurons are molecularly heterogeneous, comprising as many as fourteen distinct subtypes that show biased cell body distributions across dorsal raphe subdomains.
    1. Neuroscience

    Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy

    Ying Sun et al.
    Deep brain calcium imaging reveals the abnormal neuronal activity patterns of the amygdala GABAergic neurons in an animal model of human sleep disorder narcolepsy.

Refine your results by:

Type
Research categories