1,486 results found
    1. Cell Biology
    2. Developmental Biology

    Proliferation-independent regulation of organ size by Fgf/Notch signaling

    Agnė Kozlovskaja-Gumbrienė et al.
    Cell adhesion regulates organ size in the zebrafish lateral line system.
    1. Developmental Biology

    Localized JNK signaling regulates organ size during development

    Helen Rankin Willsey et al.
    JNK signaling is active in developing Drosophila tissues and is required for achieving proper organ size.
    1. Stem Cells and Regenerative Medicine

    Positional information specifies the site of organ regeneration and not tissue maintenance in planarians

    Eric M Hill, Christian P Petersen
    Homeostatic tissue maintenance can occur at locations distinct from the target sites of organ regeneration planarians.
    1. Developmental Biology

    Organ Size: Connecting physical cues and tissue patterning

    Damian Dalle Nogare, Ajay B Chitnis
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    1. Developmental Biology

    Altered paracrine signaling from the injured knee joint impairs postnatal long bone growth

    Alberto Roselló-Díez et al.
    Genetic analyses in mice reveal a communication system between the knee joint and the developing bones that could be explored in studies addressing evolutionary changes in body proportions and in future therapies for growth disorders.
    1. Developmental Biology

    Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

    Sobhika Agarwala et al.
    The cell junction-associated protein Amotl2a controls tissue size in the zebrafish lateral line primordium by limiting the activity of the Hippo effector Yap1 and the Wnt effector Lef1.
    1. Plant Biology

    Combining growth-promoting genes leads to positive epistasis in Arabidopsis thaliana

    Hannes Vanhaeren et al.
    Pairwise combinations of growth-promoting genes regulating distinct cellular mechanisms lead to synergistic effects on leaf growth, and hence greatly increased leaf size.
    1. Cell Biology
    2. Developmental Biology

    Spectrin regulates Hippo signaling by modulating cortical actomyosin activity

    Hua Deng et al.
    A contractile structural protein of the membrane-associated cytoskeleton is a Hippo signaling component that works through the regulation of non-muscle myosin activity in Drosophila.
    1. Stem Cells and Regenerative Medicine
    2. Human Biology and Medicine

    Organ Development: Tips from the embryonic lung

    Avinash Waghray, Jayaraj Rajagopal
    A new source of progenitor cells can now be used to study hidden aspects of human lung development and pediatric lung disease.
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    1. Cell Biology
    2. Chromosomes and Gene Expression

    Meiosis: Stopping chromosomes from breaking bad

    Rima Sandhu, G Valentin Börner
    The scaffolding that holds chromosome pairs together plays a key role in limiting the levels of double-strand breaks.
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