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    1. Cell Biology

    ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast

    Andrew Murley et al.
    Sites at which mitochondria contact the endoplasmic reticulum co-localize the replication of mitochondria and their DNA to help ensure that DNA is distributed appropriately between the newly formed organelles in cells.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Dynamic metastable long-living droplets formed by sticker-spacer proteins

    Srivastav Ranganathan, Eugene I Shakhnovich
    Multi-scale simulations reveal a potential, ATP-independent mechanism resulting in the formation of the long-living multi-droplet state by multi-valent, spacer-sticker proteins.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture

    Max Emanuel Harner et al.
    Interactions between Aim24 and the mitochondrial outer and inner membrane contact site complex (MICOS) are essential for mitochondrial ultrastructure, lipid composition and oxidative phosphorylation.
    1. Cell Biology
    2. Neuroscience

    EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling

    Catrina M Loucks et al.
    C. elegans EFHC1 influences neuronal transmission through the cilium and the synapse.
    1. Immunology and Inflammation

    Endomembrane targeting of human OAS1 p46 augments antiviral activity

    Frank W Soveg et al.
    Prenylation of human oligoadenylate synthetase 1 isoform p46 mediates endomembrane targeting and increases its antiviral activity against positive-strand RNA viruses that utilize the host endomembrane system for replication.
    1. Physics of Living Systems

    Length regulation of multiple flagella that self-assemble from a shared pool of components

    Thomas G Fai et al.
    In the microbe Chlamydomonas reinhardtii, a disassembly rate which depends on flagellar length provides an effective method to regulate the length of its two flagella.
    1. Cell Biology

    AMPK and vacuole-associated Atg14p orchestrate μ-lipophagy for energy production and long-term survival under glucose starvation

    Arnold Y Seo et al.
    Upon AMPK activation by acute glucose restriction, Atg14p shifts its distribution from ER exit sites to liquid-ordered membrane domains on the vacuolar surface where, together with Atg6p, it facilitates LD-specific autophagy (i.e., microautophagy of lipid droplets) for energy production and long-term survival of starved cells.
    1. Developmental Biology
    2. Neuroscience

    MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport

    Stephen R Tymanskyj et al.
    An under-studied microtubule-associated protein is found to regulate axon growth and branching by modulating microtubule-based organelle transport through its dual interactions with microtubules and the conventional kinesin motor.
    1. Cell Biology
    2. Physics of Living Systems

    Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells

    Saurabh Kulkarni et al.
    Embryonic and mechanical manipulations of Xenopus multiciliated epithelium reveals that cell non-autonomous tensile forces generated by embryonic elongation calibrate cilia number in multiciliated cells via a mechanosensitive ion channel, Piezo1.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A filter at the entrance of the Golgi that selects vesicles according to size and bulk lipid composition

    Maud Magdeleine et al.
    The golgin GMAP-210 captures vesicles at the cis Golgi by merely recognizing the high curvature and lipid unsaturation level of transport vesicles.