Generation of a human lung single nucleus ATAC-seq and single nucleus RNA-seq datasets reveals candidate cis-regulatory elements that advance knowledge on gene expression control in normal and diseased lungs.
Mass spectrometry exposes a post-transcriptionally regulated reduction in protein diversity in hematopoietic stem cells, including a lack of detectable Dnmt3a protein levels despite mRNA levels comparable to progenitors.
Calanoid copepods achieve efficient mate finding in turbulence through active swimming and turbulence advection, indicating that reproduction is not restricted to spatial and temporal windows of calm hydrodynamic conditions.
TRAF3, a negative regulator of noncanonical NF-κB signaling, maintains epithelial cell quiescence at confluence, and its loss triggers upregulation of immunity genes and prevents entry into G0 at high cell density.
A time-course of single nuclei RNA-seq of the mouse placenta identifies trophoblast subtypes and the genes, signaling events, and transcriptional networks important for their differentiation, maintenance, and function.