Tissue-level coordination of cardiac progenitor cells in the early mouse embryo produces a temporal compartmentalization of differentiation and morphogenesis essential for heart tube formation.
Evolutionary reconstruction of the ecdysis pathway shows that its major elements are present in the majority of metazoans, providing evidence that they originated much earlier than currently assumed.
Diverse sophisticated phylogenetic analyses update the phylogeny of the Alphaproteobacteria and show that the parasitic Holosporales is a derived group within the Rhodospirillales order which comprises primarily free-living alphaproteobacteria.
Type XVII collagen, a transmembranous protein in basal keratinocytes, suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis.
HEC transcription factors control the timing of cell fate transitions in a dynamic stem cell system, allowing plants to adapt their developmental program to diverse environments.
A physical niche for neural stem cells is generated by the induction of the immediate skin epithelium, a process triggered by the arrival of neural precursors during sensory organ formation in medaka.
Regional differences in activator and inhibitor signals alter hair cycle pace across mouse skin and produce unique fur renewal 'landscapes', with fastest renewal on the ventrum and slowest renewal on the ear pinnae.