420 results found
    1. Physics of Living Systems

    Mapping out Min protein patterns in fully confined fluidic chambers

    Yaron Caspi, Cees Dekker
    The geometry selection rules of dynamic Min protein patterns are determined in fully confined fluidic chambers, showing that both oscillations and running waves are derivatives of spiral rotations that are established as the majority pattern.
    1. Cell Biology
    2. Computational and Systems Biology

    Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration

    Alfonso Bolado-Carrancio et al.
    Different RhoA and Rac1 dynamics at the cell front and rear are coordinated through periodic GTPase waves, which define the minimal autonomous biochemical machinery necessary and sufficient for cell migration.
    1. Neuroscience

    Rotating waves during human sleep spindles organize global patterns of activity that repeat precisely through the night

    Lyle Muller et al.
    A phase-based analysis reveals wave-like spatiotemporal organization of the human sleep spindle, a brain oscillation critical to sleep-dependent memory consolidation, and elucidates its role in coordinating activity of neural networks distributed across the cortex.
    1. Neuroscience

    Cell-specific synaptic plasticity induced by network oscillations

    Shota Zarnadze et al.
    Recordings of cellular and network activities of the mouse brain provide insights into how gamma rhythms contribute to memory formation.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Nuclei determine the spatial origin of mitotic waves

    Felix E Nolet et al.
    Nuclei and spatial system dimensions control local concentrations of cell cycle regulators, determining the spatial origin of waves that coordinate​ DNA replication and, subsequently, cell division.
    1. Neuroscience

    Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves

    Miriam Schwalm et al.
    Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
    1. Physics of Living Systems

    Plasticity of cell migration resulting from mechanochemical coupling

    Yuansheng Cao et al.
    Computational and experimental studies show that different migration modes of eukaryotic cells are the result of the interplay between signaling waves and cell mechanics.
    1. Neuroscience

    Distributed rhythm generators underlie Caenorhabditis elegans forward locomotion

    Anthony D Fouad et al.
    The forward locomotor circuit of the roundworm Caenorhabditis elegans consists of multiple rhythm-generating units coupled to one another in a bidirectional manner.
    1. Neuroscience

    Synchronized excitability in a network enables generation of internal neuronal sequences

    Yingxue Wang et al.
    Hippocampal sharp-wave sequences, which are considered the key phenomenon underlying consolidation of episodic memory, are preserved even after an animal’s memory is impaired.
    1. Neuroscience

    On cross-frequency phase-phase coupling between theta and gamma oscillations in the hippocampus

    Robson Scheffer-Teixeira, Adriano BL Tort
    Phase-locking of hippocampal theta and gamma waves has been proposed to support memory formation, but an analysis using robust statistical methods finds no convincing evidence for the phenomenon.

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