2 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress

    Alexander Muir et al.
    Building on previous work (Muir et al., 2014), we validate the utility of a screen for new protein kinase substrates and define the underlying molecular basis of a new mechanism for responding to hypertonic conditions.
    1. Evolutionary Biology

    Gene family innovation, conservation and loss on the animal stem lineage

    Daniel J Richter et al.
    The genomes of animal progenitors evolved as mosaics of old, new, rearranged, and repurposed protein domains, genes and pathways and paved the way for the origin and evolution of animals.

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