Targeted mutations in a Ca2+-binding site of otoferlin, a transmembrane protein of synaptic vesicles defective in a recessive form of deafness, reveal its Ca2+ sensor role both for vesicle fusion and vesicle pool replenishment.
An unbiased transcriptomic approach reveals that developing paddlefish electrosensory organs express genes essential for mechanosensory hair cell development and synaptic transmission, and identifies candidates for mediating electroreceptor development and function.
A dynamic confrontation between Notch signalling and the transcription factor Lmx1a at the borders of the developing inner ear sensory patches regulates their segregation and the positioning of their boundaries.
The symbiotic relationship between Hydra and Chlorella is driven by metabolic co-dependence and characterized by changes in the photobiont genome in terms of lack of genes essential in free-living algae.
Cuticulosomes are organelles found in the hair cells of birds that are composed of ferritin nanoparticles, form rapidly after hatching by the fusion of vesicular structures, and may play an indirect role in magnetic sensation.