4,034 results found
    1. Developmental Biology

    Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects

    Kayleigh Bozon, Hartmut Cuny ... Sally L Dunwoodie
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    1. Cell Biology

    Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility

    Takahiro Yamanaka, Zimo Xiao ... Masayuki Shimada
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments

    Jessica Flowers, Nathaniel Echols ... Stephanie A Wankowicz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Genetics and Genomics
    2. Cancer Biology

    Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer

    Tackhoon Kim, Byung-Sun Park ... Timothy K Lu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Supralinear dendritic integration in murine dendrite-targeting interneurons

    Simonas Griesius, Amy Richardson, Dimitri Michael Kullmann
    NMDA receptors mediate prominent supralinear summation of clustered excitatory inputs to the dendrites of neurogliaform and oriens-lacunosum moleculare interneurons of the hippocampus, showing that these cells perform sub-cellular computations.
    1. Stem Cells and Regenerative Medicine

    Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

    Shiyu Zhang, Min Zhou ... Wei Zuo
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells

    Adriana K Alexander, Karina F Rodriguez ... Humphrey Hung-Chang Yao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    An image-computable model of speeded decision-making

    Paul I Jaffe, Gustavo X Santiago-Reyes ... Russell A Poldrack
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Post-retrieval noradrenergic activation impairs subsequent memory depending on cortico-hippocampal reactivation

    Hendrik Heinbockel, Gregor Leicht ... Lars Schwabe
    Impairing effects of post-retrieval noradrenergic but not glucocorticoid activation on future recall are linked to hippocampal reactivation and category-level reinstatement in ventral temporal cortex during memory retrieval.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: A genomic epidemiology study

    Gillian AM Tarr, Linda Chui ... Tim A McAllister
    E. coli O157 infections in humans are closely linked to strains circulating in local cattle populations, with some strains persisting as long as 13 years.

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